Results 181 to 190 of about 1,949,320 (295)

Death Determination, the Dying Process and the Dead Donor Rule: A Critical Analysis of the Italian 20‐Minute No‐Touch Period in Controlled Donation After Circulatory Determination of Death

Bioethics, EarlyView.
ABSTRACT In Italy, controlled Donation after Circulatory Determination of Death (cDCDD) requires a 20‐min no‐touch period documented by continuous electrocardiographic monitoring. Since Italian law adopts a single brain‐based definition of death, this procedure serves as an indirect determination of the irreversible cessation of all brain functions ...
Lucia Craxì
wiley   +1 more source

Therapeutic hypoxia to protect and revive ischemic heart and brain. [PDF]

Mil Med Res
Burtscher J, Mallet RT, Xi L, Hüfner K, Burtscher M.   +4 more
europepmc   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Aberrant Hippocampal Neurogenesis Is a Conserved Response to Stroke in Mice: A Multicenter Multimodel Study. [PDF]

Stroke
De Castro-Millán FJ, Vázquez-Reyes S, Peña-Martínez C, Rodríguez-Llave A, Parra-Pérez C, Nieto-Vaquero C, Brezzo G, Zera KA, Straus D, Goertz JE, Loppi SH, Crumpacker RR, Frye JB, Becktel DA, Dames C, Berchtold D, Fowler JH, Meisel A, Anrather J, Doyle KP, Allan SM, Buckwalter MS, McColl BW, García-Culebras A, Cuartero MI, Moro MÁ.   +25 more
europepmc   +1 more source

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, EarlyView.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Molecular and Cellular Signaling Pathways of the Effects of Hypoxia and Hypercapnia on the Mechanisms of Neuroinflammation. [PDF]

Int J Mol Sci
Chekulaev PA, Zembatov GM, Namiot ED, Alekseeva TM, Ternovykh IK, Manasova ZS, Kulikov VP, Andriutsa NS, Tregub PP.   +8 more
europepmc   +1 more source

The silent consequence of overdose: The case for brain injury‐informed opioid treatment

Addiction, EarlyView.
Nathaniel Day, Kym Kaufmann, Mauricio Garcia‐Barrera, Jitender Sareen, Daniel Vigo   +4 more
wiley   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Serendipitous Discovery of Short Peptides Dimethylammonium Salt Promoting Neural Differentiation. [PDF]

J Pept Sci
Khan SN, Shahid M, Nazir S, Bashir A, Sheikh S, Simjee SU, Maresca M, Shaheen F.   +7 more
europepmc   +1 more source