Results 281 to 290 of about 939,686 (311)

Integrative transcriptomic profiling and machine learning reveal hypoxia-associated molecular signatures for precision diagnosis in thyroid eye disease. [PDF]

Hum Genomics
Qian W, Zhu T, Liu J, Wei Y, Yang L, Fang L, Sun J, Li Y, Fang S, Zhou H.   +9 more
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Effects of fractional inspired O₂ on the O₂ pathway during submaximal and maximal exercise in male endurance athletes. [PDF]

Physiol Rep
Lehtonen E, Gagnon DD, Rissanen AE, Mikkola T, Peltonen JE.   +4 more
europepmc   +1 more source

Automated hypoxia and apnea identification for neonates via enhanced respiratory signal modeling with deep learning. [PDF]

Sci Rep
Krupa AJD, Chauhan B, Azam SKS, Anand SA, Bereznychenko V, R N, Dhanalakshmi S.   +6 more
europepmc   +1 more source

Acute and chronic effects of plyometric exercise performed with hypoxia on post-activation performance enhancement (PAPE). [PDF]

PLoS One
Coskun B, Hamlin MJ.
europepmc   +1 more source

Tankyrases modulate the hypoxia response through non-catalytic mechanisms affecting HIF-1α. [PDF]

Cell Commun Signal
Zamudio-Martínez E, Delgado-Bellido D, Borrego-Pérez J, Garcia-Diaz A, Herrera-Campos AB, Rodríguez-Vargas JM, Oliver FJ.   +6 more
europepmc   +1 more source

Use of Echocardiography Under Hypoxic Stress Without Exercise to Assess Right to Left Shunting. [PDF]

J Cardiovasc Dev Dis
Villa Etchegoyen C, Wraith RE, Brown LS, Breznak KK, Mital R, Lester SJ, Ayoub C, Alsidawi S, Shipman JN, Farina JM, Arsanjani R, Stepanek J.   +11 more
europepmc   +1 more source

A novel protein cPFKFB4 encoded by hsa_circ_0065394 strengthens PKM2-mediated glucose metabolic reprogramming to facilitate pancreatic cancer progression under hypoxia. [PDF]

Mol Cancer
Chen H, Li M, Xie F, Liu S, Yang A, Yin J, Wang X, Long Y, Wu S, Cai L, Chen J, Wang H.   +11 more
europepmc   +1 more source