Results 131 to 140 of about 97,129 (264)

Physiological responses to hypoxia are constrained by environmental temperature in heterothermic tenrecs

, 2023
Maiah E. M. Devereaux, Claudia Silva Rubio, Frank van Breukelen, Matthew E. Pamenter   +3 more
openalex   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Comparative analysis of liver transcriptome reveals adaptive responses to hypoxia environmental condition in Tibetan chicken. [PDF]

Anim Biosci
Cao Y, Zeng T, Han W, Ma X, Gu T, Chen L, Tian Y, Xu W, Yin J, Li G, Lu L, Gun S.   +11 more
europepmc   +1 more source

Acute environmental hypoxia potentiates satellite cell‐dependent myogenesis in response to resistance exercise through the inflammation pathway in human

, 2019
Florian Britto, Olouyoumi Gnimassou, Estelle De Groote, Estelle Balan, Geoffrey Warnier, Amandine Everard, Patrice D. Cani, Louise Deldicque   +7 more
openalex   +2 more sources

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Naked mole-rats employ a normoxic escape behaviour that is altered by social interaction. [PDF]

Biol Lett
Lashani P, Lamontagne G, Kadamani KL, Pamenter ME.   +3 more
europepmc   +1 more source

Acclimatory responses of the Daphnia pulex proteome to environmental changes. I. Chronic exposure to hypoxia affects the oxygen transport system and carbohydrate metabolism [PDF]

, 2009
Bettina Zeis, Tobias Lamkemeyer, Rüdiger J. Paul, Frank Nunes, Susanne Schwerin, Marita Koch, Wolfgang Schütz, Johannes Madlung, Claudia Fladerer, Ralph Pirow   +9 more
openalex   +1 more source

Data from 'Disparate inventories of hypoxia gene sets across corals align with inferred environmental resilience'

, 2022
Rachel Alderdice, Benjamin C. C. Hume, Michael Kühl, Mathieu Pernice, David J. Suggett, Christian R. Voolstra   +5 more
openalex   +1 more source

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

Advanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source

Transgenerational adaptation to hypoxia. [PDF]

Sci Adv
Kim K, Telger A, Sarkar G, Surya S, Rothi MH, Meers MP, Wang SY, Greer EL.   +7 more
europepmc   +1 more source