Results 161 to 170 of about 4,650,121 (384)

Hypoxia’s Impact on Hippocampal Functional Connectivity: Insights from Resting-State fMRI Studies

Brain Sciences
The hippocampus is one of the brain’s most vulnerable structures to hypoxia, playing a crucial role in memory and spatial navigation. This sensitivity makes it a key region for understanding the effects of hypoxia on brain connectivity.
Julia Micaux, Abir Troudi Habibi, Franck Mauconduit, Marion Noulhiane   +3 more
doaj   +1 more source

Distinct Tumor Microenvironment at Tumor Edge as a Result of Astrocyte Activation Is Associated With Therapeutic Resistance for Brain Tumor

Frontiers in Oncology, 2019
Tumor vasculatures and hypoxia are critical tumor micro-environmental factors associated with tumor response to the therapy and heterogeneous in both time- and location-dependent manner.
Chiu-Min Lin, Ching-Fang Yu, Ching-Fang Yu, Hsueh-Ya Huang, Hsueh-Ya Huang, Fang-Hsin Chen, Fang-Hsin Chen, Fang-Hsin Chen, Ji-Hong Hong, Ji-Hong Hong, Ji-Hong Hong, Chi-Shiun Chiang, Chi-Shiun Chiang, Chi-Shiun Chiang   +13 more
doaj   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

Bioelectrical Interfaces Beyond Excitable Cells: Cancer, Aging, and Gene Expression Modulation

Advanced Materials Interfaces, EarlyView.
ABSTRACT The investigation of biological conductivity has evolved from its classical foundation based on ionic fluxes underpinning cardiac and neuronal excitability to a multifaceted regulator of cellular physiology. Traditional approaches for probing electrical events in living matter focused largely on action potentials recording.
Paolo Cadinu, Matthew K. Burgess, Catarina Franco Jones, Marzia Iarossi, Manuel Schröter, Nako Nakatsuka, Mustafa B. A. Djamgoz, Gil Gonçalves, Sidahmed Abayzeed, Paola Sanjuán‐Alberte, Paula M. Mendes, Frankie J. Rawson, Malavika Nair, Michael Levin, Rosalia Moreddu   +14 more
wiley   +1 more source

The effect of hypoxia on Daphnia magna performance and its associated microbial and bacterioplankton community: a scope for Genotype x Microbial community interactions upon environmental stress ? [PDF]

, 2023
Manon Coone, Isabel Vanoverberghe, Shira Houwenhuyse, Chris Verslype, Ellen Decaestecker   +4 more
openalex   +1 more source

Looking for Resistance to Soft Rot Disease of Potatoes Facing Environmental Hypoxia

International Journal of Molecular Sciences
Plants are exposed to various stressors, including pathogens, requiring specific environmental conditions to provoke/induce plant disease. This phenomenon is called the “disease triangle” and is directly connected with a particular plant–pathogen interaction.
Tomasz Maciag, Edmund Kozieł, Katarzyna Otulak-Kozieł, Sylwia Jafra, Robert Czajkowski   +4 more
openaire   +2 more sources

Bioresorbable Mo–W Electrodes: Toward an Extended Operational Lifetime Through Controlled Alloying and Oxide Coating Engineering

Advanced Materials Interfaces, EarlyView.
Bioresorbable electrochemical sensors face instability in biofluids. Although alloys can mitigate rapid in vivo dissolution, Mo–W remains underexplored for sensing. This work engineers Mo–W films with a nanocrystalline oxide coating, improving stability and enabling reliable oxygen and pH sensing for up to 10 days, highlighting their potential for ...
C. Fernandes, Filippo Franceschini, Kitty Baert, Jon Ustarroz, I. Taurino   +4 more
wiley   +1 more source

Hypoxia causes woodlice (Porcellio scaber) to select lower temperatures and impairs their thermal performance and heat tolerance.

PLoS ONE, 2019
Environmental temperatures and oxygen availability are important for the balance between oxygen supply and demand. Terrestrial organisms are generally perceived to be less limited by access to oxygen than their aquatic counterparts.
Andrzej Antoł, Wiktoria Rojek, Sanjeev Singh, Damian Piekarski, Marcin Czarnoleski   +4 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source