Results 131 to 140 of about 9,128 (213)

Trial protocol: DOLFIN trial: Developmental Outcomes of Long-term Feed Supplementation in Neonates—A UK multicentre, blinded, stratified, randomised controlled trial

Trials
Background Infants born extremely preterm (EP; < 28 weeks of gestation) or term born infants with hypoxic-ischemic encephalopathy (HIE) have increased risk of long-term cognitive and learning deficits.
Morag J. Andrew, Nicholas Embleton, Pollyanna Hardy, Samantha Johnson, Edmund Juszczak, Heather Ledbury, Claire Pearson, Oliver Rivero-Arias, Adriana Amorim Francisco, Janet Berrington, Penny Bradley, Peter J. Bradley, Christina Cole, Kate Court, Madeleine Hurd, Andrew King, Louise Linsell, David Murray, Heather M. O’Connor, Charles C. Roehr, Victoria Stalker, Kayleigh Stanbury, Usharani Devi Wahengbam, Richard Welsh, Joy Wiles, Jeremy R. Parr   +25 more
doaj   +1 more source

HbA1c improvement in pregnant women with type 1 diabetes using the CamAPS FX automated insulin delivery (AID) system: Clinical and economic outcomes

Diabetic Medicine, EarlyView.
Clinical and economic benefits of using CamAPS FX pregnancy‐specific AID system. Abstract Aims The Automated Insulin Delivery among Pregnant women with Type 1 diabetes (AiDAPT) trial demonstrated that using the CamAPS FX automated insulin delivery (AID) was associated with improved glycaemic outcomes.
Maria‐Eleni Syleouni, Tara T. M. Lee, Federica Carrieri, Eleanor M. Scott, Aesha Khan Mirón, Helen R. Murphy   +5 more
wiley   +1 more source

Multimodal predictor of neurodevelopmental outcome in newborns with hypoxic-ischaemic encephalopathy

, 2015
Automated multimodal prediction of outcome in newborns with hypoxic-ischaemic encephalopathy is investigated in this work. Routine clinical measures and 1h EEG and ECG recordings 24h after birth were obtained from 38 newborns with different grades of HIE.
Doyle, Orla, Temko, Andriy, Murray, Deirdre, Boylan, Geraldine, Marnane, William, Lightbody, Gordon   +5 more
core   +1 more source

Redefining mild hypoxic‐ischaemic encephalopathy: A fundamental step to therapeutic progress

Developmental Medicine &Child Neurology, EarlyView.
Jeanie L. Y. Cheong
wiley   +1 more source

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai, Thomas Forbes, Simon A. Carter, Alison L. Kent, Chanel Prestidge, David T. Selewski, Eveline Staub, Anke Raaijmakers   +7 more
wiley   +1 more source

Dietary N‐Acetylserotonin offers protection against Shewanella putrefaciens infection in Chinese mitten crab Eriocheir sinensis

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Shewanella putrefaciens is an important bacterial pathogen that poses a serious threat to Chinese mitten crab (Eriocheir sinensis) aquaculture. However, the protective effects of N‐Acetylserotonin (NAS) against S. putrefaciens infection in E. sinensis remain unknown.
Xiuxian Zhang, Yiyao Liu, Xurui Zheng, Meiling Liu, Li He, Sijia Chen, Haipeng Cao, Chunlei Gai, Weidong Ye   +8 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy

Annals of Neurology, Volume 100, Issue 1, Page 109-122, July 2026.
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva, Karen Herbert, Lakshmi Balaji, Jia Mei He, Tejaswi Kandula, Hugo A. Sampaio, Hooi‐Ling Teoh, Esther Tantsis, Jihee Sohn, Nancy Briggs, Nickson Ning, Matthew C. Kiernan, Didu S. Kariyawasam, Michelle A. Farrar   +13 more
wiley   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Multiple Carboxylase Deficiency in an Infant Presenting With Severe Metabolic Acidosis and Sepsis‐Like Features: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Multiple carboxylase deficiency (MCD) is a rare, treatable inborn error of biotin metabolism that may present in children in the first year of life with life‐threatening metabolic crises. We report a 4‐month‐old child presenting with persistent seizures, eczematous rash near the orifices, unjustified loss of hair with baldness, and severe ...
Touqeer Rehman, Riyan Saeed, Muhammad Ahmed Akif Rauf, Luqman Asif, Muhammad Junaid, Muddassir Khalid, Rao Nouman Ali, Umair Ali, Fred Segawa   +8 more
wiley   +1 more source