Results 51 to 60 of about 48,292 (244)

Hypothermia for hypoxic–ischemic encephalopathy [PDF]

open access: yesExpert Review of Obstetrics & Gynecology, 2010
Moderate to severe hypoxic-ischemic injury in newborn infants, manifested as encephalopathy immediately or within hours after birth, is associated with a high risk of either death or a lifetime with disability. In recent multicenter clinical trials, hypothermia initiated within the first 6 postnatal hours has emerged as a therapy that reduces the risk ...
C Michael, Cotten, Seetha, Shankaran
openaire   +2 more sources

Automated Neuroprognostication Via Machine Learning in Neonates with Hypoxic‐Ischemic Encephalopathy

open access: yesmedRxiv
Neonatal hypoxic‐ischemic encephalopathy is a serious neurologic condition associated with death or neurodevelopmental impairments. Magnetic resonance imaging (MRI) is routinely used for neuroprognostication, but there is substantial subjectivity and ...
John D. Lewis   +8 more
semanticscholar   +1 more source

Treating Seizures after Hypoxic-Ischemic Encephalopathy—Current Controversies and Future Directions

open access: yesInternational Journal of Molecular Sciences, 2021
Seizures are common in newborn infants with hypoxic-ischemic encephalopathy and are highly associated with adverse neurodevelopmental outcomes. The impact of seizure activity on the developing brain and the most effective way to manage these seizures ...
Kelly Q. Zhou   +7 more
semanticscholar   +1 more source

Hypoxic-ischemic encephalopathy, intraventricular hemorrhage in the fetus and newborn

open access: yesКлинический разбор в общей медицине, 2023
The article presents a clinical observation of a newborn with hypoxic-ischemic encephalopathy and intraventricular hemorrhage.
Aleksandra N. Balakina   +2 more
doaj   +1 more source

Whole-Blood Gene Expression Profile After Hypoxic-Ischemic Encephalopathy

open access: yesJAMA Network Open
This case-control study compares the genome expression at birth and associated outcome in neonates with hypoxic-ischemic encephalopathy in a high-income country (Italy) and their counterparts in low- to middle-income countries (India, Sri Lanka, and ...
P. Montaldo   +18 more
semanticscholar   +1 more source

Association of NOS3 gene variants and clinical contributors of hypoxic-ischemic encephalopathy

open access: yesBrazilian Journal of Medical and Biological Research, 2014
The aim of this study was to analyze the association of different clinical contributors of hypoxic-ischemic encephalopathy with NOS3 gene polymorphisms.
R. Kuzmani? ?amija   +7 more
doaj   +1 more source

Mimicking Hypoxic-Ischemic Encephalopathy in a Newborn with 21q Deletion Originating from Ring Chromosome 21

open access: yesChildren, 2023
Partial deletion of the long arm (q) in chromosome 21 is an extremely rare condition with various phenotypes, including microcephaly, neurodevelopmental delay, dysmorphic features, and epileptic seizures. Neonatal hypoxic-ischemic encephalopathy (HIE) is
Ja Un Moon, Sook Kyung Yum
doaj   +1 more source

Pathophysiology of Cerebral Hyperperfusion in Term Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review for Future Research

open access: yesFrontiers in Pediatrics, 2021
Worldwide neonatal hypoxic-ischemic encephalopathy (HIE) is a common cause of mortality and neurologic disability, despite the implementation of therapeutic hypothermia treatment.
D. G. Kleuskens   +7 more
semanticscholar   +1 more source

Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa   +15 more
wiley   +1 more source

Pathophysiology of Perinatal Asphyxia in Humans and Animal Models

open access: yesBiomedicines, 2022
Perinatal asphyxia is caused by lack of oxygen delivery (hypoxia) to end organs due to an hypoxemic or ischemic insult occurring in temporal proximity to labor (peripartum) or delivery (intrapartum).
Daniel Mota-Rojas   +5 more
doaj   +1 more source

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