Results 171 to 180 of about 20,402 (269)

Neonatal Acute Kidney Injury—An Australian and New Zealand Perspective

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long‐term implications for survival, kidney function, and long‐term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular ...
Saumil Desai   +7 more
wiley   +1 more source

Dietary N‐Acetylserotonin offers protection against Shewanella putrefaciens infection in Chinese mitten crab Eriocheir sinensis

open access: yesJournal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract Shewanella putrefaciens is an important bacterial pathogen that poses a serious threat to Chinese mitten crab (Eriocheir sinensis) aquaculture. However, the protective effects of N‐Acetylserotonin (NAS) against S. putrefaciens infection in E. sinensis remain unknown.
Xiuxian Zhang   +8 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy

open access: yesAnnals of Neurology, Volume 100, Issue 1, Page 109-122, July 2026.
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva   +13 more
wiley   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2028-2048, July 2026.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

The role of endotoxin, the TNF family of cytokines and intracellular pH in perinatal hypoxic-ischemic brain injury

open access: yes, 2010
To explore the effect of endotoxin as a sensitising agent prior to neonatal hypoxiaischemia differing doses of endotoxin (E. coli lipopolysaccharide, LPS) were given to neonatal mice prior to hypoxia-ischemia, with sensitising effects noted at dosages ...
Kendall, G.
core  

Multiple Carboxylase Deficiency in an Infant Presenting With Severe Metabolic Acidosis and Sepsis‐Like Features: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Multiple carboxylase deficiency (MCD) is a rare, treatable inborn error of biotin metabolism that may present in children in the first year of life with life‐threatening metabolic crises. We report a 4‐month‐old child presenting with persistent seizures, eczematous rash near the orifices, unjustified loss of hair with baldness, and severe ...
Touqeer Rehman   +8 more
wiley   +1 more source

Early versus late amniotomy during twin labor

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 152-160, July 2026.
Abstract Objective This study evaluates whether timing of amniotomy affects labor characteristics and maternal and neonatal outcomes in twin deliveries. Methods This retrospective study was conducted at a single academic medical center and included dichorionic diamniotic (DCDA) twin pregnancies with a normal anomaly scan and a vertex‐presenting leading
Or Eliner   +5 more
wiley   +1 more source

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