Results 41 to 50 of about 661,093 (139)

Sestrin2 Exerts a Novel Protective Effect Against LPS‐Induced Ferroptosis via the Nrf2–SLC7A11–GPX4 Signaling Axis

open access: yesThe FASEB Journal, Volume 39, Issue 22, 30 November 2025.
This graphical abstract shows that LPS downregulates SESN2, leading to suppressed GPX4 activity, increased ROS, lipid peroxidation, and inflammation. SESN2 overexpression reverses these effects by activating the Nrf2/SLC7A11/GPX4 axis, reducing MDA and 4HNE levels, preserving redox balance, and alleviating ocular symptoms including hypopyon and retinal
Xuerui Zhang   +16 more
wiley   +1 more source

A Novel Semi‐Automated Pipeline for Optimizing 3D‐Printed Drug Formulations

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel, semi‐automated deep learning and differential evolution pipeline designed for generating medicines for 3D‐printed medicines is introduced. This pipeline successfully generates a diverse range of drug formulations with an 80% printing success rate and 92% accuracy in predicting printing parameters.
Youssef Abdalla   +8 more
wiley   +1 more source

Wind Derivatives: Modeling and Pricing [PDF]

open access: yes, 2013
Wind is considered to be a free, renewable and environmentally friendly source of energy. However, wind farms are exposed to excessive weather risk since the power production depends on the wind speed, the wind direction and the wind duration.
Zapranis, Achilleas   +1 more
core   +1 more source

Derivatives at Agricultural Banks [PDF]

open access: yes
Using data between 1995 and 2010, we find that agricultural banks are benefiting from the derivatives activities by reducing total risk without hurting their profit.
Hartarska, Valentina M., Shen, Xuan
core  

USE OF HYPROMELLOSE AND HYDROXYPROPYL CELLULOSE TO DEVELOP AN AGE APPROPRIATE PLATFORM TECHNOLOGY FOR THE ADMINISTRATION OF MEDICINES TO CHILDREN [PDF]

open access: yes
There is a significant need for research and development into paediatric medicines. The absence of suitable medicines or critical safety and efficacy information, poses significant risks to a particularly vulnerable patient population.
Ernest, T
core   +1 more source

Credit derivatives: an overview [PDF]

open access: yes
Arising from financial institutions' need to hedge and diversify credit risk, credit derivatives have now become a major investment tool. Almost all credit derivatives take the form of the credit default swap, which transfers default risk from one party ...
David Mengle
core  

Hypromellose functionality in film-forming solutions: In vitro characterization and in silico optimization for topical administration of ketoprofen

open access: yes
This study investigated the development of hypromellose-based film-forming solutions (FFSs) containing keto- profen, aiming to elucidate how key formulation variables (concentration and type of hypromellose (high-vis- cosity grades 2910 and 2208 ...
Đekić, Ljiljana   +4 more
core   +1 more source

Bio-Dis and the Paddle Dissolution Apparatuses Applied to the Release Characterization of Ketoprofen from Hypromellose Matrices

open access: yes, 2009
The purposes of this work were: (1) to comparatively evaluate the effects of hypromellose viscosity grade and content on ketoprofen release from matrix tablets, using Bio-Dis and the paddle apparatuses, (2) to investigate the influence of the pH of the ...
PEZZINI, Bianca Ramos   +1 more
core  

Options, Futures, and Other Derivatives in Russia: An Overview [PDF]

open access: yes
This work provides a descriptive overview of Russian markets for financial derivatives. Available figures for the exchange-traded and over-the-counter-traded derivatives in Russia show that the Russian derivatives markets experienced enormous growth ...
Rotfuß, Waldemar
core  

Should We Fear Derivatives? [PDF]

open access: yes
This paper discusses the extent to which derivatives pose threats to firms and to the economy. After reviewing the derivatives markets and putting in perspective the various measures of the size of these markets, the paper shows who uses derivatives and ...
Rene M. Stulz
core  

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