The clinical, EEG, and radiological findings in 6 patients with the asymmetric variant of hypsarrhythmia among 26 children with infantile spasms are reported from the University of Michigan EEG Laboratory, Ann Arbor, MI.
J Gordon Millichap
doaj +3 more sources
Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome [PDF]
BackgroundInfantile epileptic spasm syndrome (IESS), a rare age-specific epileptic encephalopathy, exhibits limited therapeutic efficacy, with approximately 50% of patients showing resistance to adrenocorticotropic hormone (ACTH) monotherapy.
Ka-Na Lin +9 more
doaj +2 more sources
Hypsarrhythmia Variant Patterns
The frequency of hypsarrhythmia variant or atypical patterns was determined by analysis of pre-ACTH EEG records of 53 consecutive patients with infantile spasms at Children’s Hospital, Harvard Medical School, Boston, MA.
J Gordon Millichap
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Hypsarhythmia or Hypsarrhythmia?
Hypsarhythmia was originally spelled with one ‘r’ by Drs Frederick and Erna Gibbs when they coined the term in 1952.
John J. Millichap, J. Gordon Millichap
doaj +4 more sources
Distributed EEG source localization of hypsarrhythmia in west syndrome: a standardized, low-resolution, brain electromagnetic tomography (sLORETA) study [PDF]
Background West syndrome is a developmental epileptic encephalopathy characterized by epileptic spasms, hypsarrhythmia, and neurodevelopmental regression.
Jooyoung Lee +6 more
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Brain tumours as an unrecognized etiology of infantile epileptic spasms syndrome (IESS): The role of resective epilepsy surgery [PDF]
Brain tumours are a rare cause of infantile epileptic spasm syndrome (IESS). Epilepsy surgery may be utilized in refractory IESS due to tumours, although reports are limited.
Rowan Pentz +10 more
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Short-Term Outcomes and Immunologic Mechanisms of Adrenocorticotropic Hormone in Infantile Epileptic Spasm Syndrome: A Multicenter Prospective Trial in Southern China [PDF]
Introduction Adrenocorticotropic hormone (ACTH) is a first-line drug and standard therapy in infantile epileptic spasm syndrome (IESS) with different response rates. The mechanism of ACTH for treatment of IESS remains incompletely understood.
Yanping Ran +15 more
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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]
BackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen +13 more
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Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]
IntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Linghui Zhu +8 more
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Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]
Epileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
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