Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]
Frontiers in PediatricsBackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen +13 more
doaj +2 more sources
Infantile Spasms, Hypsarrhythmia, and Adrenoleukodystrophy (ALD)
Pediatric Neurology Briefs, 1988 An 8 1/2 month-old girl with seizures beginning at 5 days, hypsarrhythmia in the EEG, severe retardation, and a clinical diagnosis of infantile spasms was discovered to have biochemical and pathological features of adrenoleukodystrophy, as reported from ...
J Gordon Millichap
doaj +2 more sources
Short-Term Outcomes and Immunologic Mechanisms of Adrenocorticotropic Hormone in Infantile Epileptic Spasm Syndrome: A Multicenter Prospective Trial in Southern China [PDF]
Neurology and TherapyIntroduction Adrenocorticotropic hormone (ACTH) is a first-line drug and standard therapy in infantile epileptic spasm syndrome (IESS) with different response rates. The mechanism of ACTH for treatment of IESS remains incompletely understood.
Yanping Ran +15 more
doaj +2 more sources
Novel case of resolution of hypsarrhythmia following tuber resection in a patient with infantile spasms and tuberous sclerosis [PDF]
Clinical Case Reports, 2017 Key Clinical Message This article describes a case involving the resolution of hypsarrhythmia, a generalized abnormal EEG pattern, following focal resection of a cortical tuber in a patient with tuberous sclerosis.
Robert Marsh +2 more
doaj +2 more sources
Congenital rubella associated with hypsarrhythmia. [PDF]
Archives of Disease in Childhood, 1976 A child with acute lymphoblastic leukaemia complicated by prolonged gastrointestinal and skin haemorrhages due to profound thrombocytopenia finally died of thrombotic occlusions of major cerebral arteries due to mucormycosis. Biopsy of any suspect lesion is needed urgently before prolonged therapy with amphotericin B is started.
R K, Oates, D, Harvey
openaire +4 more sources
Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]
Frontiers in PediatricsIntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Linghui Zhu +8 more
doaj +2 more sources
ACTH Therapy in Epileptic Spasms without Hypsarrhythmia
Pediatric Neurology Briefs, 2005 The short and long-term effects of adrenocorticotrophic hormone (ACTH) in 30 children ages 11 to 86 months (median 29 months) with epileptic spasms (ES) without hypsarrhythmia were analyzed at Tokyo Women’s Medical University, Japan.
J Gordon Millichap
doaj +2 more sources
Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]
Annals of Indian Academy of NeurologyEpileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
doaj +2 more sources
Connectivity Analysis of Hypsarrhythmia-EEG for Infants With West Syndrome
IEEE Transactions on Neural Systems and Rehabilitation EngineeringDetection of hypsarrhythmia electroencephalography (EEG) in infants with West syndrome (WS) is currently performed by manual inspection of long-term video/EEG recording, producing low inter-rater reliability.
Di Lian +10 more
doaj +2 more sources
Interictal EEG features as computational biomarkers of West syndrome [PDF]
Frontiers in PediatricsBackgroundWest syndrome (WS) is a devastating epileptic encephalopathy with onset in infancy and early childhood. It is characterized by clustered epileptic spasms, developmental arrest, and interictal hypsarrhythmia on electroencephalogram (EEG ...
Jiaqing Li +5 more
doaj +2 more sources