Identification of Hypsarrhythmia in Children with Microcephaly Infected by Zika Virus [PDF]
Hypsarrhythmia is an electroencephalographic pattern specific to some epileptic syndromes that affect children under one year of age. The identification of this pattern, in some cases, causes disagreements between experts, which is worrisome since an ...
Gean Carlos Sousa+6 more
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Asymmetric Hypsarrhythmia: Clinical Electroencephalographic and Radiological Findings [PDF]
Twenty-six children (16 boys and 10 girls) with hypsarrhythmia and infantile spasms (IS) were studied at the University of Michigan EEG Laboratory in a 4-year period.
Bobele GB+17 more
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Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome [PDF]
BackgroundInfantile epileptic spasm syndrome (IESS), a rare age-specific epileptic encephalopathy, exhibits limited therapeutic efficacy, with approximately 50% of patients showing resistance to adrenocorticotropic hormone (ACTH) monotherapy.
Ka-Na Lin+9 more
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Congenital rubella associated with hypsarrhythmia. [PDF]
A child with acute lymphoblastic leukaemia complicated by prolonged gastrointestinal and skin haemorrhages due to profound thrombocytopenia finally died of thrombotic occlusions of major cerebral arteries due to mucormycosis. Biopsy of any suspect lesion is needed urgently before prolonged therapy with amphotericin B is started.
D Harvey, R K Oates
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Clinical Profile of Infants with Hypsarrhythmia [PDF]
The present study was done in order to obtain a baseline profile of infantile spasms and associated neurological disorders.The study included 50 patients with infantile spasm in Queen Rania Hospital for children in Jordan. The following data were obtained: sex, age at onset of spasms, details of seizure, family history of epilepsy, significant pre ...
Wael Khreisat
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Oral Prednisolone vs. IM Corticotropin and Hypsarrhythmia* in West Syndrome [PDF]
Investigators at University of Columbo, Sri Lanka, studied the efficacy of oral prednisolone (40-60 mg/day) and intramuscular adrenocorticotrophin hormone (40-60 IU synthetic ACTH every other day) for 14 days in improving hypsarrhythmia in children (age ...
J Gordon Millichap, John J Millichap
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Hypsarrhythmia in epileptic spasms: Synchrony in chaos [PDF]
Hypsarrhythmia is an electroencephalographic pattern associated with epileptic spasms and West syndrome. West syndrome is a devastating epileptic encephalopathy, originating in infancy. Hypsarrhythmia has been deemed to be the interictal brain activity, while the electrodecremental event associated with the spasms is denoted as the ictal event.
Vera Nenadovic+3 more
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Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]
Epileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
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Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]
IntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Linghui Zhu+8 more
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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]
BackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen+13 more
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