Results 1 to 10 of about 174,637 (308)

I kappa B kinase interacting protein as a promising biomarker in pan-cancer: A multi-omics analysis [PDF]

open access: yesFrontiers in Genetics, 2023
Background: Human chromosome 12 contains I kappa B kinase interacting protein (IKBIP) is also commonly known as IKIP. The involvement of IKBIP in the growth of tumors has only been discussed in a small number of publications.Purpose: To explore the role ...
Chenyang Bi   +9 more
doaj   +4 more sources

Investigating the Role of I Kappa B Kinase ε in the Pathogenesis of Psoriasis

open access: yesActa Dermato-Venereologica, 2019
is missing (Short communication)
Isabella Weimar   +3 more
doaj   +5 more sources

Anti-inflammatory effects of Torin2 on lipopolysaccharide-treated RAW264.7 murine macrophages and potential mechanisms

open access: yesHeliyon, 2022
Context: Torin2 has various pharmacological properties. However, its anti-inflammatory activity has not been reported. Objective: This study focused on the potential anti-inflammatory properties of Torin2 in lipopolysaccharide (LPS)-evoked RAW264.7 ...
Shanshan Wei   +5 more
doaj   +1 more source

Case of a Male Newborn with Incontinentia Pigmenti Initially Misdiagnosed as a Recurrent Skin Infection [PDF]

open access: yesNeonatal Medicine, 2020
Incontinentia pigmenti (IP), also known as Bloch-Sulzberger syndrome, is a rare X-linked dominant disorder that is generally lethal to males and almost always leads to death in utero.
Sang Ho Park, Kyung-Hwa Nam, Yo Han Ho
doaj   +1 more source

Changes of Signaling Pathways in Hypothalamic Neurons with Aging

open access: yesCurrent Issues in Molecular Biology, 2023
The hypothalamus is an important regulator of autonomic and endocrine functions also involved in aging regulation. The aging process in the hypothalamus is accompanied by disturbed intracellular signaling including insulin/insulin-like growth factor-1 ...
Petr M. Masliukov
doaj   +1 more source

Constitutive phosphorylation of I kappa B alpha by casein kinase II. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1995
The NF-kappa B/Rel proteins are sequestered in the cytoplasm in association with the phosphorylated form of I kappa B alpha. Upon induction with a wide variety of agents, the activity of NF-kappa B/Rel proteins is preceded by the rapid degradation of I kappa B alpha protein.
C F, Barroga   +3 more
openaire   +2 more sources

Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion

open access: yesNeural Regeneration Research, 2019
Shuxuetong injection composed of leech (Hirudo nipponica Whitman) and earthworm (Pheretima aspergillum) has been used for the clinical treatment of acute stroke for many years in China.
Zuo-Yan Sun   +8 more
doaj   +1 more source

Pharmacological Effects of Agastache rugosa against Gastritis Using a Network Pharmacology Approach

open access: yesBiomolecules, 2020
Agastache rugosa is used as a Korean traditional medicine to treat gastric diseases. However, the active ingredients and pharmacological targets of A. rugosa are unknown. In this study, we aimed to reveal the pharmacological effects of A.
Hyeon-Hwa Nam   +8 more
doaj   +1 more source

Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling.

open access: yesPLoS ONE, 2010
BackgroundI-kappa B kinase 2 (IKK2 or IKK-beta) is one of the most crucial signaling kinases for activation of NF-kappa B, a transcription factor that is important for inflammation, cell survival and differentiation.
Kalsoom Sughra   +3 more
doaj   +1 more source

Identification of Bioactive Natural Product from the Stems and Stem Barks of Cornus walteri: Benzyl Salicylate Shows Potential Anti-Inflammatory Activity in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

open access: yesPharmaceutics, 2021
Cornus walteri (Cornaceae), known as Walter’s dogwood, has been used to treat dermatologic inflammation and diarrheal disease in traditional oriental medicine. As part of an ongoing research project to discover natural products with biological activities,
Dahae Lee   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy