Semaphorin 7A interacts with nuclear factor NF-kappa-B p105 via integrin β1 and mediates inflammation [PDF]
Cell Communication and Signaling, 2023 Semaphorin7a (SEMA7A), a membrane-anchored member of the semaphorin protein family, could be involved in a diverse range of immune responses via its receptor integrin β1.
Xuan Li +8 more
doaj +2 more sources
TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway [PDF]
Cells, 2018 Non-canonical NF-κB signalling plays important roles in the development and function of the immune system but it also is deregulated in a number of inflammatory diseases.
Laura D’Ignazio +2 more
doaj +5 more sources
The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma [PDF]
BMC Cancer, 2009 Background Gambogic acid (GA) is a major active ingredient of gamboge, a widely used traditional Chinese medicine that has been reported to be a potent cytotoxic agent against some malignant tumors.
Zhou Xiaojian +9 more
doaj +4 more sources
Asterias rubens: Evidence of NF-kappa B genes. [PDF]
Meta Gene, 2016 In the present paper we show a survey of the Asterias rubens sea star genome for genes associated with NF-kappa-B proteins implied in the immune response. The NF-kappa B gene, into 2 subunits, was found in this invertebrate.
Leclerc M, Kresdorn N, Horres R.
europepmc +3 more sources
Broussonetia papyrifera Root Bark Extract Exhibits Anti-inflammatory Effects on Adipose Tissue and Improves Insulin Sensitivity Potentially Via AMPK Activation [PDF]
, 2020 The chronic low-grade inflammation in adipose tissue plays a causal role in obesity-induced insulin resistance and its associated pathophysiological consequences. In this study, we investigated the effects of extracts of Broussonetia papyrifera root bark
Choi, Jang Hyun +9 more
core +1 more source
How the venom from the ectoparasitoid wasp Nasonia vitripennis exhibits anti-inflammatory properties on mammalian cell lines [PDF]
, 2014 With more than 150,000 species, parasitoids are a large group of hymenopteran insects that inject venom into and then lay their eggs in or on other insects, eventually killing the hosts.
Danneels, Ellen +6 more
core +9 more sources
Epicatechin induces NF-kappa B, activator rotein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells [PDF]
, 2009 The dietary flavonoid epicatechin has been reported to exhibit a wide range of biological activities. The objective of the present study was to investigate the time-dependent regulation by epicatechin on the activity of the main transcription factors (NF-
Bravo, Laura +5 more
core +4 more sources
Subunit-Specific Role of NF-κB in Cancer
Biomedicines, 2018 The transcription factor NF-κB is a key player in inflammation, cancer development, and progression. NF-κB stimulates cell proliferation, prevents apoptosis, and could promote tumor angiogenesis as well as metastasis.
Barbara Kaltschmidt +3 more
doaj +1 more source
The Effect of Open Reading Frame 3 of Hepatitis E virus on Cellular NF-κB Activity [PDF]
Basrah Journal of Veterinary Research, 2023 NF-B (Nuclear Factor Kappa B) is a crucial transcription factor that is essential for host survival during pathogen infection in animal and human. Therefore, it has been a main goal for numerous pathogens to modify cellular NF-κB activity to create
Rana Abdulnabi +2 more
doaj +1 more source
Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation [PDF]
, 1994 The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To examine this notion in more detail, we determined the protein
Baltimore, David +3 more
core +1 more source