Results 191 to 200 of about 174,637 (308)

Therapeutic Potential of Ruberythric Acid in Intestinal Inflammation and Barrier Function Reduction. [PDF]

Prev Nutr Food Sci
Jo HJ, Kim S, Jung SK.
europepmc   +1 more source

Regulatory B cells in the central nervous system: From immune regulation to neuroprotection

Neuroprotection, EarlyView.
Neuroinflammatory mechanisms and the therapeutic potential of regulatory B cells (Bregs). Following brain Injury (left panel) blood–brain barrier disruption facilitates the infiltration of peripheral leukocytes, including effector B cells (Beff) and effector T cells (Teff). This process triggers the activation of macrophages, astrocytes, and microglia,
Luiza Stanaszek, Miroslaw Janowski
wiley   +1 more source

Cedrol ameliorates ulcerative colitis <i>via</i> myeloid differentiation factor 2-mediated inflammation suppression, with barrier restoration and microbiota modulation. [PDF]

World J Gastroenterol
Zhao YQ, Zhang Y, Qin Y, Zhang RY, Wang JP.   +4 more
europepmc   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source

Context-dependent impact of type I interferon signaling in cancer. [PDF]

Mol Cancer
Ruiz-Iglesias A, Guilbaud E, Galluzzi L, Mañes S.   +3 more
europepmc   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Insulin resistance induced by obesity: Mechanisms, metabolic implications and therapeutic approaches. [PDF]

Mol Biol Rep
Choo YN, Ravi RN, Subramaniyan V.
europepmc   +1 more source

[18F] PSMA PET‐CT and [18F] Choline PET‐CT in the Diagnosis of High‐Risk Localized Prostate Cancer: Comparation of Both Tests

The Prostate, EarlyView.
ABSTRACT Background To compare choline PET‐CT and PSMA PET‐CT in a cohort of patients with high‐risk localized prostate cancer, assessing the diagnostic capacity of both tests. whose therapeutic approach could be modified based on the results. Methods An observational study was conducted in 116 patients with high‐risk prostate cancer between January ...
M. A. Tárraga‐Honrubia, A. S. Salinas‐Sánchez, S. Navarro‐Jiménez, M. V. Lorenzo‐Sánchez, P. Carrión‐López, J. M. Giménez‐Bachs   +5 more
wiley   +1 more source

Endotoxin retention in adipose tissue leading to persistent hypotension in catecholamine-dependent acute obstructive suppurative cholangitis. [PDF]

J Transl Int Med
Li K, Zhu S, Ye C, Ding Y, Liu J, Wang Y, Wang Z, Li W, Yang D, Wang X, Lin R, Shi B.   +11 more
europepmc   +1 more source