Results 281 to 290 of about 174,637 (308)
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I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function.
Journal of immunology (Baltimore, Md. : 1950), 2002NF-kappaB is a transcription factor that regulates a variety of genes involved in the control of the immune and inflammatory responses. Activation of NF-kappaB is mediated by an inducible I-kappaB kinase (IKK) complex comprised of two catalytic subunits, IKKalpha and IKKbeta. In this study, the role of these kinases in the development and function of T
Hong, Ren +3 more
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Journal of immunology (Baltimore, Md. : 1950), 2005
BCR signaling is propagated by a series of intermediaries and eventuates in NF-kappaB activation, among other outcomes. Interruption of several mediators that constitute the signalosome, such as PI3K and phospholipase Cgamma2, completely blocks BCR signaling for NF-kappaB.
Takuya, Mizuno, Thomas L, Rothstein
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BCR signaling is propagated by a series of intermediaries and eventuates in NF-kappaB activation, among other outcomes. Interruption of several mediators that constitute the signalosome, such as PI3K and phospholipase Cgamma2, completely blocks BCR signaling for NF-kappaB.
Takuya, Mizuno, Thomas L, Rothstein
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Journal of immunology (Baltimore, Md. : 1950), 2005
Rheumatoid arthritis (RA) causes a symmetric, inflammatory polyarthritis that results in joint destruction and significant disability. Signaling pathways that regulate the production of cytokines and destructive enzymes have been implicated in its pathogenesis and represent potential therapeutic targets.
Susan E, Sweeney +3 more
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Rheumatoid arthritis (RA) causes a symmetric, inflammatory polyarthritis that results in joint destruction and significant disability. Signaling pathways that regulate the production of cytokines and destructive enzymes have been implicated in its pathogenesis and represent potential therapeutic targets.
Susan E, Sweeney +3 more
openaire +1 more source
Thrombosis and haemostasis, 2003
Activated platelets alter endothelial chemotactic and adhesive properties. Transient interaction of alpha-thrombin-activated platelets with endothelial cells is sufficient to induce secretion of the NF-kappa B-regulated chemokine MCP-1. To evaluate upstream signaling events in platelet-induced NF-kappa B activation, we compared the effect of platelets,
Meinrad, Gawaz +7 more
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Activated platelets alter endothelial chemotactic and adhesive properties. Transient interaction of alpha-thrombin-activated platelets with endothelial cells is sufficient to induce secretion of the NF-kappa B-regulated chemokine MCP-1. To evaluate upstream signaling events in platelet-induced NF-kappa B activation, we compared the effect of platelets,
Meinrad, Gawaz +7 more
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Journal of immunology (Baltimore, Md. : 1950), 1999
NF-kappa B plays a critical role in the transcriptional regulation of proinflammatory gene expression in various cells. Cytokine-mediated activation of NF-kappa B requires activation of various kinases, which ultimately leads to the phosphorylation and degradation of I kappa B, the NF-kappa B cytoplasmic inhibitor. The food derivative curcumin has been
C, Jobin +6 more
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NF-kappa B plays a critical role in the transcriptional regulation of proinflammatory gene expression in various cells. Cytokine-mediated activation of NF-kappa B requires activation of various kinases, which ultimately leads to the phosphorylation and degradation of I kappa B, the NF-kappa B cytoplasmic inhibitor. The food derivative curcumin has been
C, Jobin +6 more
openaire +1 more source
Broadband convolutional processing using band-alignment-tunable heterostructures
Nature Electronics, 2022Pengfei Wang, Shi-Jun Liang, Xing Zhou
exaly
Pseudospin-selective Floquet band engineering in black phosphorus
Nature, 2023Shaohua Zhou, Changhua Bao
exaly