Results 81 to 90 of about 24,397,514 (310)

A General Representation Theorem for Integrated Vector Autoregressive Processes [PDF]

open access: yes
We study the algebraic structure of an I(d) vector autoregressive process, where d is restricted to be an integer. This is useful to characterize its polynomial cointegrating relations and its moving average representation, that is to prove a version of ...
Massimo Franchi
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Biological Nanoparticles for Enhancing Chronic Wound Regeneration

open access: yesCells
Chronic wounds (CWs) represent a growing global health concern with profound clinical and socioeconomic implications. Studies indicate that approximately 15% of CWs remain unhealed one year after the initial treatment.
Daniil Zotikov   +8 more
doaj   +1 more source

Two approaches toward constrained vector optimization and identity of the solutions [PDF]

open access: yes
In this paper we deal with a Fritz John type constrained vector optimization problem. In spite that there are many concepts of solutions for an unconstrained vector optimization problem, we show the possibility “to double” the number of concepts when a ...
Rocca Matteo   +2 more
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Identification and genotyping of Chikungunya virus using reverse transcription polymerase chain reaction and restriction fragment length polymorphism methods

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Chikungunya virus (CHIKV) genotyping involves sequencing fractions of genes encoding E1, E2, and nsP1 proteins or the entire genome of the virus.
N. A. Netesova   +6 more
doaj   +1 more source

Vector Winter 2012 [PDF]

open access: yes, 2011
Contents: Letter from the Editors -- Science Fiction or Science Face? -- More Social, More Connected -- The Audience's New Groove -- Feel the Drama -- The Future of Engineering -- Knowing Unclear -- Utopia or Not -- VectortainmentVector is the ...
University of Texas at Austin
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Elevated Plasmodium Sporozoite Infection Rates in Primary and Secondary Malaria Vectors in Anopheles stephensi-Infested Areas of Ethiopia

open access: yesInsects
Assessing bloodmeal sources and sporozoite infection rates in mosquito vectors is essential for understanding their role in malaria transmission. This study investigated these factors in Hawassa, Southern Ethiopia—an area recently invaded by Anopheles ...
Dawit Hawaria   +14 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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