The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV) [PDF]
In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines.
Butter, Colin +4 more
core +1 more source
Pathogenicity and molecular characterization of infectious bursal disease virus in China
: Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious disease, resulting in considerable economic losses in the world poultry industry.
Jiamin Lian +9 more
doaj +1 more source
A Recombinant Newcastle Disease Virus (NDV) Expressing VP2 Protein of Infectious Bursal Disease Virus (IBDV) Protects against NDV and IBDV [PDF]
ABSTRACT Infectious bursal disease virus (IBDV) causes a highly immunosuppressive disease in chickens. Currently available, live IBDV vaccines can lead to generation of variant viruses. We have developed an alternative vaccine that will not create variant IBDV. By using the reverse genetics approach, we devised a recombinant Newcastle disease
Zhuhui, Huang +3 more
openaire +2 more sources
Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]
BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P +6 more
core +3 more sources
Preliminary structural analysis of infectious bursal disease virus by cryo-electron microscopy
In order to investigate the structure of infectious bursal disease virus (IBDV) and how the double-stranded RNA (dsRNA) segments of IBDV are organized inside its capsid and how the genome segments are transcribed and assembled, we first obtained IBDV ...
MIAO Miao +5 more
doaj +1 more source
Isolation and genomic characteristics of the novel variant infectious bursal disease virus in China
The infectious bursal disease virus (IBDV) is a member of the viruses that can induce immunosuppression in chickens. In recent years, more and more IBDV-infected cases by the novel variant IBDV were reported in China, and it has been demonstrated that ...
Zongyi Bo +11 more
doaj +1 more source
Evaluation of secondary metabolites of herbal plant extracts as an antiviral effect on infectious bursal disease virus isolates in embryonated chicken eggs [PDF]
Background and Aim: Infectious bursal disease attacks the poultry industry, mainly young chickens, causing immunosuppression, and death with high economic losses. This study aimed to evaluate the effects of the monoextract, diextracts, and triextracts of
Rawaa Saladdin Jumaa +2 more
doaj +1 more source
Simultaneous detection of vaccinal and field infectious bursal disease viruses in layer chickens challenged with a very virulent strain after vaccination [PDF]
Infectious bursal disease virus is an important poultry pathogen. It is distributed worldwide and causes significant economic losses. In this study, a system was adopted for the simultaneous monitoring of vaccine and virulent strains using reverse ...
Dobrosavljević, Ivan +4 more
core +1 more source
Infectious bursal disease Virus (IBDV) specific reverse transcriptase/polymerase chain recation (RT/PCR) positive 40 broiler bursa fabricius samples obtained from a commercially reared flock were investigated for genetic diversity by PCR-RFLP assay.
G. Ozbes, H.B. Ertas, A. Muzo
doaj +1 more source
Modeling Infectious Bursal Disease Virus (IBDV) Antigenic Drift In Vitro
Infectious bursal disease virus (IBDV) vaccines do not induce sterilizing immunity, and vaccinated birds can become infected with field strains. Vaccine-induced immune selection pressure drives the evolution of antigenic drift variants that accumulate amino acid changes in the hypervariable region (HVR) of the VP2 capsid, which may lead to vaccine ...
Amin S. Asfor +5 more
openaire +4 more sources

