Results 51 to 60 of about 2,333 (171)

Chicken Infectious Anemia Virus Markedly Enhances the Pathogenicity of Infectious Bronchitis Virus–Infected Chickens

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Chicken infectious anemia virus (CIAV) and infectious bronchitis virus (IBV) represent two of the most economically significant pathogens in the global poultry production. In recent years, coinfections involving CIAV and IBV have become increasingly prevalent in clinical scenarios across Southern China and globally.
Hao Chen, Shuangshuang Ma, Liuyang Yuan, Hongchun Yang, Shijun Xu, Shufeng Feng, Yaping Wang, Aobo Xu, Xiaoran Xuan, Ziqi Ling, Yang Li, Hongbin Si, Gonghe Li, Changbo Ou, Fabian Lean   +14 more
wiley   +1 more source

Vaccine‐Associated Recombination and Virulence Heterogeneity of GI‐19 (QX Type) Infectious Bronchitis Virus in Eastern and Southern China, 2024−2025

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Infectious bronchitis (IB) virus (IBV) remains a major pathogen threatening the poultry industry. Its rapid mutation and recombination continuously generate variants that disseminate worldwide. Between May 2024 and February 2025, 49 field strains were isolated from chickens vaccinated with live‐attenuated IBV vaccines (H120, 4/91, or QXL87) in four ...
Zijian Dai, Yuanlu Lu, Lulu Deng, Yan Luo, Yiran Zeng, Yusen Tian, Xianchen Meng, Haitao Zhang, Jihui Ping, Nan-hua Chen   +9 more
wiley   +1 more source

PROTECTION ACTIVITY OF T CELL LYMPHOKINES AGAINST INFECTIOUS BURSAL DISEASE IN LAYER PULLETS

The Iraqi Journal of Agricultural science, 2023
The present study was aimed to administering hyperimmunized avian salmonella-immune lymphokines (S-ILK) to 200 one-day-old layer pullets to improve the immunological response against Gumboro (IBDV) divided into four groups.
Mushtaq T. B. Al-Zuhariy
doaj   +1 more source

Beyond FoxP3—Identification of a Chicken Regulatory T Cell Signature

European Journal of Immunology, Volume 55, Issue 12, December 2025.
Chicken FOXP3+ putative regulatory T cells were identified using both bulk and single‐cell RNA sequencing to define their transcriptional signature and flow cytometry to confirm surface marker expression. This combined approach revealed a distinct putative Treg subset characterized by CD4, CD25, and GITR surface expression. ABSTRACT Regulatory T cells (
Isabell Naumann, Edward S. Ricemeyer, Daniel Elleder, Jiri Plachy, Dominik von La Roche, Kim Vučinić, Thomas W. Göbel, Bernd Kaspers, Simon P. Früh, Sonja Härtle   +9 more
wiley   +1 more source

The Power of Yeast

Yeast, Volume 42, Issue 12, Page 303-310, December 2025.
ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Herpesvirus of Turkey Recombinant Viruses Expressing Infectious Bursal Disease Virus (IBDV) VP2 Immunogen Induce Protection against an IBDV Virulent Challenge in Chickens

Virology, 1995
Two recombinant herpesviruses of turkey (HVT) expressing the VP2 protein of infectious bursal disease virus (IBDV or Gumboro disease virus) have been constructed: vHVT001 and vHVT002. The VP2 open reading frame was inserted at the locus of the small subunit of ribonucleotide reductase gene (HSV-1 UL40 homolog) without any exogenous promoter in vHVT001 ...
Darteil, Raphaël, Bublot, Michel, Laplace, Eliane, Bouquet, Jean-François, Audonnet, Jean-Christophe, Rivière, Michel   +5 more
openaire   +2 more sources

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, Volume 12, Issue 33, September 4, 2025.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source

Chicken IL-17 as a potent adjuvant enhances IBDV VP2 DNA vaccine immunogenicity and protective efficacy

Poultry Science
Infectious bursal disease virus (IBDV) is an important immunosuppressive virus in chickens, which caused an acute and highly contagious infectious disease and resulted in considerable economic losses in the world poultry industry.
Jianlou Zhang, Wenyan Li, Shanshan Huo, Xiaojing Xin, Liyue Wang   +4 more
doaj   +1 more source

Comparative Safety, Immunogenicity, and Efficacy of CEF Cell-Based and DF-1 Cell Line Adapted Infectious Bursal Disease Vaccines in Specific-Pathogen-Free Chickens

Journal of Immunology Research, 2022
Infectious bursal disease (IBD) is an immunosuppressive and economically important disease of young chickens caused by infectious bursal disease virus (IBDV). The National Veterinary Institute (Bishoftu, Ethiopia) produces intermediate IBDV vaccine using
Daniel Workineh, Molalegne Bitew, Daniel Oluwayelu, Belayneh Getachew, Takele Abayneh, Esayas Gelaye, Hawa Mohammed, Tedros Fikru, Mastewal Birhan, Bereket Dessalegn, Getaw Deresse, Kassaye Adamu, Saddam Mohammed Ibrahim   +12 more
doaj   +1 more source