Results 71 to 80 of about 3,761 (205)

Vaccine‐Associated Recombination and Virulence Heterogeneity of GI‐19 (QX Type) Infectious Bronchitis Virus in Eastern and Southern China, 2024−2025

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Infectious bronchitis (IB) virus (IBV) remains a major pathogen threatening the poultry industry. Its rapid mutation and recombination continuously generate variants that disseminate worldwide. Between May 2024 and February 2025, 49 field strains were isolated from chickens vaccinated with live‐attenuated IBV vaccines (H120, 4/91, or QXL87) in four ...
Zijian Dai, Yuanlu Lu, Lulu Deng, Yan Luo, Yiran Zeng, Yusen Tian, Xianchen Meng, Haitao Zhang, Jihui Ping, Nan-hua Chen   +9 more
wiley   +1 more source

Examination of macroscopic and microscopic lesions in IBDV-infected organs and molecular characterization of IBDV VP1 gene fragments obtained from commercial broiler farms in Indonesia

Veterinary World, 2023
Background and Aim: Infectious bursal disease (IBD) is an infectious immunosuppressive disease that affects young chickens. Instead of strict biosecurity practices, vaccination is used to control IBD. However, the disease has not been effectively managed. Variations in the observed clinical symptoms lead to confounding diagnoses.
Bernike Anggun Damairia, Khrisdiana Putri, Michael Haryadi Wibowo   +2 more
openaire   +3 more sources

Beyond FoxP3—Identification of a Chicken Regulatory T Cell Signature

European Journal of Immunology, Volume 55, Issue 12, December 2025.
Chicken FOXP3+ putative regulatory T cells were identified using both bulk and single‐cell RNA sequencing to define their transcriptional signature and flow cytometry to confirm surface marker expression. This combined approach revealed a distinct putative Treg subset characterized by CD4, CD25, and GITR surface expression. ABSTRACT Regulatory T cells (
Isabell Naumann, Edward S. Ricemeyer, Daniel Elleder, Jiri Plachy, Dominik von La Roche, Kim Vučinić, Thomas W. Göbel, Bernd Kaspers, Simon P. Früh, Sonja Härtle   +9 more
wiley   +1 more source

Molecular characterization of field infectious bursal disease virus isolates from Nigeria [PDF]

Veterinary World, 2016
Aim: To characterize field isolates of infectious bursal disease virus (IBDV) from outbreaks in nine states in Nigeria through reverse transcription polymerase chain reaction (RT-PCR) and sequence analysis of portions of the VP2 and VP1 genes and to ...
Ijeoma O. Nwagbo, Ismaila Shittu, Chika I. Nwosuh, George O. Ezeifeka, Frederick J. C. Odibo, Linda O. Michel, Daral J. Jackwood   +6 more
doaj   +1 more source

Efficient assembly of full-length infectious clone of Brazilian IBDV isolate by homologous recombination in yeast [PDF]

, 2014
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia e Terapia Experimental.
Silva Jr., J. V. J., Bertani, G. R., Santos, H. F., Trevisol, I. M., Gil, L. H. V. G., Almeida-Queiroz, S. R., Silva, A. N. M. R., Arenhart, S.   +7 more
core   +1 more source

The Power of Yeast

Yeast, Volume 42, Issue 12, Page 303-310, December 2025.
ABSTRACT Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—particularly Saccharomyces cerevisiae—as both a model organism and a cell factory.
Jens Nielsen
wiley   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Detection of IBDV-specific protein expressed from synthetically assembled IBDV RNPs.

, 2014
(A) Detection of VP2 and VP4 polypeptides by indirect IF. BSC40 cells were infected with VT7-VP1, VT7-VP3 or VT7LacOI, or coinfected with VT7-VP1 and VT7-VP3, and then incubated with 2% FCS-DMEM containing 2 mM IPTG to induce recombinant protein ...
José F. Rodríguez (303494), Romy M. Dalton (516983)   +1 more
core   +1 more source

The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling

Advanced Science, Volume 12, Issue 33, September 4, 2025.
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu, Suhui He, Wen Shi, Jinxia Xu, Shiyang Liu, Zexu Yu, Danyue Li, Qiao Jin, Yumeng Wang, Zian Zhang, Qian Lv, Yuanxiang Ge, Yunjie Li, Xinyue Li, Nan Chen, Xinyu Fu, Yang Yang, Fushan Shi   +17 more
wiley   +1 more source

Evasion of maternal antibody protection by an IBDV Argentine variant

Poultry Science
Infectious bursal disease (IBD) is a viral disease that affects the ability of chickens to produce humoral immune responses. One way to prevent the disease is the passage of maternally derived antibodies (MDA) from dams to offsprings via the yolk. Despite sanitary measures, which include immunization with genogroup 1 (G1) vaccines, infections with IBDV
Juan Jaton, Evangelina Gómez, María Soledad Lucero, Lucía Rizzi, María José Gravisaco, Silvina Pinto, Analía Berinstein, Silvina Chimeno Zoth   +7 more
openaire   +4 more sources