Results 41 to 50 of about 3,761 (205)

Protection from infectious bursal disease virus (IBDV)-induced immunosuppression by immunization with a fowlpox recombinant containing IBDV-VP2

open access: yesAvian Pathology, 2003
Immunosuppression resulting from infectious bursal disease virus (IBDV) infection has critical health and welfare implications for birds, yet it is incompletely understood and largely overlooked as a measure of vaccine efficacy. The ability of a fowlpoxvirus recombinant (fpIBD1) containing the VP2 protein of IBDV to protect against IBDV-induced ...
Colin Butter   +3 more
openaire   +3 more sources

Validation and application of RT-qPCR methods for the quantification of gene expression of inflammatory mediators in chickens infected with different IBDV genotypes.

open access: yes, 2023
openLo studio si propone di validare e applicare metodiche di RT-qPCR per la quantificazione dell'espressione genica di mediatori dell'infiammazione in polli infettati con diversi genotipi di IBDV (Virus della malattia di Gumboro).
CONDORELLI, ALESSANDRO
core  

Characterization and pathogenicity of infectious bursal disease virus in Southern China

open access: yesPoultry Science, 2022
: Infectious bursal disease virus (IBDV) is a widespread pathogen that induces immunosuppression in 3 to 6-wk-old chickens, casuing great threaten to the poultry industry worldwide.
Zixian Chen   +5 more
doaj   +1 more source

Chicken PRMT3 facilitates IBDV replication

open access: yesPoultry Science
Protein arginine methyltransferases (PRMTs) in mammals play a role in various signaling pathways, such as virus infection, inflammasome responses, and cancer growth. While some PRMTs have been found to regulate interferon production in mammals, the mechanism in chickens remains to be fully understood. This study focused on investigating the function of
Zhixuan Xiong   +9 more
openaire   +3 more sources

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Experimental co-infection of variant infectious bursal disease virus and fowl adenovirus serotype 4 increases mortality and reduces immune response in chickens

open access: yesVeterinary Research, 2021
Infectious bursal disease virus (IBDV) and fowl adenovirus serotype 4 (FAdV-4) cause infectious bursal disease (IBD) and hydropericardium-hepatitis syndrome, respectively.
A-hui Xu   +5 more
doaj   +1 more source

Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure

open access: yes, 2002
Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life. Wild-type serotype 1 IBDV strains
Peeters, B.P.H.   +6 more
core   +1 more source

Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Advances in avian diagnostic pathology integrate histopathology, immunohistochemistry, molecular diagnostics and digital pathology to enhance the detection and management of poultry diseases. Emerging tools, including machine learning and artificial intelligence, further improve diagnostic accuracy, disease surveillance and outbreak prediction.
Gebyaw Menge Getnet   +2 more
wiley   +1 more source

gga-miR-155 Enhances Type I Interferon Expression and Suppresses Infectious Burse Disease Virus Replication via Targeting SOCS1 and TANK

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by IBD virus (IBDV). MicroRNAs (miRNAs) are involved in host-pathogen interactions and innate immune response to viral infection. However, the role
Bin Wang   +18 more
doaj   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

open access: yesAdvanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras   +6 more
wiley   +1 more source

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