Vaccine, 2015 Bluetongue is a disease of ruminants caused by the bluetongue virus (BTV). Bluetongue outbreaks can be controlled by vaccination, however, currently available vaccines have several drawbacks.
Femke Feenstra, Piet A Van Rijn
exaly +4 more sources
Identification of the NLS and NES motifs of VP2 from chicken anemia virus and the interaction of VP2 with mini-chromosome maintenance protein 3 [PDF]
BMC Veterinary Research, 2012 Background VP2 of chicken anemia virus (CAV) is a dual-specificity phosphatase required for virus infection, assembly and replication. The functions of the nuclear localization signal (NLS) and nuclear export signal (NES) of VP2 in the cell, however, are
Cheng Jai-Hong +6 more
doaj +5 more sources
Mutational analysis of human norovirus VP2 elucidates critical molecular interactions for virus assembly [PDF]
Journal of VirologyHuman noroviruses (HuNoVs) are the leading cause of viral gastroenteritis, with ≥80% of infections caused by the GII genogroup. HuNoVs are non-enveloped, with an icosahedral capsid composed of 90 dimers of the major capsid protein VP1, which encloses a ...
Janam J. Dave +5 more
doaj +3 more sources
Preliminary Study of Radioiodination of VP2
Journal of Isotopes, 2016 The VP2 peptide specifically binding to vasoactive intestinal polypeptide receptor 1(VPAC1) receptor was radioiodinated with 131I by bi-functional linker N-succinimidyl 5-(tributylstannyl)-3-pyridinecarboxylate (SPC), and in vitro and in vivo stability ...
MA Huan +5 more
doaj +3 more sources
Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry [PDF]
EMBO Journal, 1998 A complex of the polyomavirus internal protein VP2/VP3 with the pentameric major capsid protein VP1 has been prepared by co-expression in Escherichia coli. A C-terminal segment of VP2/VP3 is required for tight association, and a crystal structure of this segment, complexed with a VP1 pentamer, has been determined at 2.2 A resolution.
Xiaojiang S Chen +2 more
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Conserved rotavirus NSP5 and VP2 domains interact and affect viroplasm [PDF]
Journal of Virology, 2020 One step of the life cycle common among all rotaviruses (RV) studied so far is the formation of viroplasms, membrane-less cytosolic inclusions providing a microenvironment for early morphogenesis and RNA replication.
Ackermann, Mathias; https://orcid.org/ +5 more
core +5 more sources
Vaccines, 2023 Porcine parvovirus 1 (PPV1) is one of the most prevalent pathogens that can cause reproductive disorder in sows. The VP2 protein of PPV1 is the most important immunogenic protein that induces neutralizing antibodies and protective immunity.
Huawei Zhang +2 more
exaly +3 more sources
Chicken infectious anemia virus exploits host CK2α as an essential factor for its replication via VP2 Ser182/Asp183-mediated interaction [PDF]
Journal of VirologyChicken infectious anemia virus (CIAV) induces severe immunosuppression in chickens. The nonstructural protein VP2 of CIAV is shown to play critical roles in viral assembly and viral replication.
Ziyue Ma +6 more
doaj +2 more sources
Vaccines, 2022 The increased virulence of infectious bursal disease virus (IBDV) is a threat to the chicken industry. The construction of novel herpesvirus of turkey-vectored (HVT) vaccines expressing VP2 of virulent IBDV may be a promising vaccine candidate for ...
Abid Ullah Shāh +2 more
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Development of a virtual phantom for HDR cervical cancer brachytherapy: A multi‐institutional tool for training, quality assurance, and variability reduction [PDF]
Journal of Applied Clinical Medical Physics, Volume 27, Issue 6, June 2026.Background High‐dose‐rate brachytherapy (HDR‐BT) is a critical modality in the treatment of cervical cancer, requiring accurate and efficient treatment planning. Unlike external beam radiation therapy, HDR‐BT demands specialized skills and training.
Kotaro Iijima +10 more
wiley +2 more sources