Results 21 to 30 of about 49,884 (215)

Poliovirus Mutants at Histidine 195 of VP2 Do Not Cleave VP0 into VP2 and VP4 [PDF]

Journal of Virology, 1999
ABSTRACT The final stage of poliovirus assembly is characterized by a cleavage of the capsid precursor protein VP0 into VP2 and VP4. This cleavage is thought to be autocatalytic and dependent on RNA encapsidation. Analysis of the poliovirus empty capsid structure has led to a mechanistic model for VP0 cleavage involving a conserved histidine ...
M, Hindiyeh, Q H, Li, R, Basavappa, J M, Hogle, M, Chow   +4 more
openaire   +2 more sources

Detection of a new canine parvovirus mutant in Iran [PDF]

Iranian Journal of Veterinary Medicine, 2018
BACKGROUND: Canine Parvovirus (CPV) is one of the major causes of fatal gastroenteritis in young dogs. After emergence of CPV-2, two new variants were reported and named CPV-2a and CPV-2b. In 2001 the newest variant was reported and named CPV-2c.
Gholamraza Nikbakhat, Shahram Shahram, Shahaboldin Mohyedidini   +2 more
doaj   +1 more source

Recombinant Virus-like Particles of Human Parvovirus B19 with the Internal Location of VP1 Unique Region Produced by Hansenula polymorpha

Viruses, 2022
Human parvovirus B19 (HPV B19) is pathogenic to human, which can cause fifth disease, transient aplastic crisis, arthritis, myocarditis, autoimmune disorders, hydrops fetalis, and so on.
Shuai Shao, Qingqing Wang, Yuqin Jin, Xuefeng Zhang, Zhaoming Liu, Shi Chen, Hailan Wu, Sensen Yang, Fang Tang, Jiguo Su, Yu Liang, Jing Zhang, Qiming Li   +12 more
doaj   +1 more source

Typing of Human Enterovirus by Partial Sequencing of VP2 [PDF]

Journal of Clinical Microbiology, 2007
ABSTRACT The sequencing of the VP1 hypervariable region of the human enterovirus (HEV) genome has become the reference test for typing field isolates. This study describes a new strategy for typing HEV at the serotype level that uses a reverse transcription-PCR assay targeting the central part of the VP2 capsid protein. Two pairs
Nasri, Dorsaf, Bouslama, Lamjed, Omar, Shabir, Saoudin, Henia, Bourlet, Thomas, Aouni, Mahjoub, Pozzetto, Bruno, Pillet, Sylvie   +7 more
openaire   +4 more sources

Construction and Evaluation of the Immunogenicity and Protective Efficacy of Recombinant Replication-Deficient Human Adenovirus-5 Expressing Genotype VII Newcastle Disease Virus F Protein and Infectious Bursal Disease Virus VP2 Protein

Vaccines, 2023
Newcastle disease (ND) and infectious bursal disease (IBD) are two key infectious diseases that significantly threaten the health of the poultry industry.
Ting Xu, Ting Xiong, Wenting Xie, Jing Wu, Xiao Liu, Guimin Li, Yadi Lv, Linyu Li, Zekun Yang, Han Wang, Dingxiang Liu, Ruiai Chen   +11 more
doaj   +1 more source

Expression of recombinant 35 kDa fragment of VP2 protein of canine parvovirus using Escherichia coli expression system [PDF]

Veterinary World, 2021
Background and Aim: Canine parvovirus (CPV) is one of the most common viral infections in dogs, causing acute hemorrhagic gastroenteritis and high mortality. Vaccination effectively prevents CPV infection.
Natnaree Inthong, Sarawan Kaewmongkol, Nattakan Meekhanon, Eukote Suwan, Wanat Sricharern, Khomson Satchasataporn, Rungthiwa Sinsiri, Kaitkanoke Sirinarumitr, Theerapol Sirinarumitr   +8 more
doaj   +1 more source

Myristylated polyomavirus VP2: role in the life cycle of the virus [PDF]

Journal of Virology, 1990
The double-stranded genome of the small DNA tumor virus, polyomavirus, is enclosed in a capsid composed of a major protein, VP1, which associates as pentameric capsomeres into an icosahedral structure, and two minor proteins, VP2 and VP3, whose functions and positions within the structure are unknown.
Krauzewicz, Nina, Streuli, C. H., Stuart-Smith, N., Jones, M. D., Wallace, Susan, Griffin, Beverly E.   +5 more
openaire   +3 more sources

Mutations in the VP2 gene of rotavirus associated with benzimidazole sensitivity

Virus Research, 2021
Rotavirus species A (RVA) is the etiological agent of acute gastroenteritis in young individuals of various animal species, including humans. Vaccination has helped to reduce the impact of these viruses on humans and some species of domestic mammals, but they do not confer complete immunity, so antirotavirus agents are another important control option.
Fernando, Chávez-Maya, Gary, García-Espinosa, María Eugenia, López-Arellano, Luis, Padilla-Noriega   +3 more
openaire   +2 more sources

Recovery of Recombinant Canine Distemper Virus That Expresses CPV-2a VP2: Uncovering the Mutation Profile of Recombinant Undergoing 50 Serial Passages In Vitro

Frontiers in Cellular and Infection Microbiology, 2022
Canine distemper and canine parvoviral enteritis are infections caused by the canine distemper virus (CDV) and canine parvovirus type 2 (CPV-2), respectively.
Fuxiao Liu, Jiahui Lin, Qianqian Wang, Youming Zhang, Hu Shan   +4 more
doaj   +1 more source

Novel Polyomaviruses in Mammals from Multiple Orders and Reassessment of Polyomavirus Evolution and Taxonomy

Viruses, 2019
As the phylogenetic organization of mammalian polyomaviruses is complex and currently incompletely resolved, we aimed at a deeper insight into their evolution by identifying polyomaviruses in host orders and families that have either rarely or not been ...
Bernhard Ehlers, Augustin E. Anoh, Nicole Ben Salem, Sebastian Broll, Emmanuel Couacy-Hymann, Daniela Fischer, Alma Gedvilaite, Nanina Ingenhütt, Sonja Liebmann, Maite Martin, Arsene Mossoun, Lawrence Mugisha, Jean-Jacques Muyembe-Tamfum, Maude Pauly, Bernat Pérez de Val, Hannah Preugschas, Dania Richter, Grit Schubert, Claudia A. Szentiks, Tamara Teichmann, Cornelia Walter, Rainer G. Ulrich, Lidewij Wiersma, Fabian H. Leendertz, Sébastien Calvignac-Spencer   +24 more
doaj   +1 more source