TRIM25 knockdown/knockout enhances IBDV replication.
(A-B) Validation of the optimal siRNA targeting TRIM25 by Western blotting (A) and RT-qPCR (B). (A) HEK293T cells were co-transfected with siRNAi (siTRIM25-1, siTRIM25-2, siTRIM25-3, and negative siRNA control siSc.) and pFlag-TRIM25, and the expression ...
Aijing Liu (662185) +21 more
core +1 more source
Development of diagnostic tools for IBDV detection using plants as bioreactors [PDF]
AbstractInfectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric particles with different architectures based on the capsid protein VP2 have been widely produced for different purposes.
Evangelina Gómez +5 more
openaire +5 more sources
Preliminary structural analysis of infectious bursal disease virus by cryo-electron microscopy
In order to investigate the structure of infectious bursal disease virus (IBDV) and how the double-stranded RNA (dsRNA) segments of IBDV are organized inside its capsid and how the genome segments are transcribed and assembled, we first obtained IBDV ...
MIAO Miao +5 more
doaj +1 more source
Key role of TLR3 in type I IFN expression and apoptosis induction in IBDV-infected chicken fibroblast cells. [PDF]
Infectious Bursal Disease Virus (IBDV) (Avibirnavirus genus, Birnaviridae family) is a non-enveloped virus with a double-stranded RNA (dsRNA) genome.
Diaz-Beneitez E +7 more
europepmc +2 more sources
Isolation and genomic characteristics of the novel variant infectious bursal disease virus in China
The infectious bursal disease virus (IBDV) is a member of the viruses that can induce immunosuppression in chickens. In recent years, more and more IBDV-infected cases by the novel variant IBDV were reported in China, and it has been demonstrated that ...
Zongyi Bo +11 more
doaj +1 more source
Molecular insights of recently circulated Infectious Bursal Disease Virus (IBDV) in broiler chicken in Egypt [PDF]
IBDV is still one of the most important causes of significant economic losses in poultry industry in Egypt, although implementation of the intensive vaccination programs.
Gabr El-Bagoury +3 more
doaj +1 more source
A Recombinant Newcastle Disease Virus (NDV) Expressing VP2 Protein of Infectious Bursal Disease Virus (IBDV) Protects against NDV and IBDV [PDF]
ABSTRACT Infectious bursal disease virus (IBDV) causes a highly immunosuppressive disease in chickens. Currently available, live IBDV vaccines can lead to generation of variant viruses. We have developed an alternative vaccine that will not create variant IBDV. By using the reverse genetics approach, we devised a recombinant Newcastle disease
Zhuhui, Huang +3 more
openaire +2 more sources
PD-1 induces autophagy via the PI3K/AKT/FoxO1 pathway to promote infectious bursal disease virus replication. [PDF]
IntroductionAutophagy is an important process in host cell responses to viral replication and spread, including those against infectious bursal disease virus (IBDV).
Zhang Q +11 more
europepmc +2 more sources
Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive avian disease caused by IBD virus (IBDV). Cell apoptosis triggered by IBDV contributes to the dysfunction of immune system in host.
Yao Qin +17 more
doaj +1 more source
Isolation and Pathotyping of Infectious Bursal Disease Virus (IBDV) from Field Outbreaks among Chickens in Egypt [PDF]
Infectious bursal disease (IBD) is a main health problem causing considerable economic losses in poultry flocks in Egypt. Throughout 2018-2019, bursae samples were assembled from different chicken's farms localized in four Egyptian governorates (Giza ...
Samar El-Masry +2 more
doaj +1 more source

