We exposed chicken embryos at embryonating day (ED18) to a cell-adapted very virulent strain of IBDV (ca- vvIBDV) and original vvIBDV and examined the apoptosis from infected bursa of Fabricius (BF) and thymus organs.
Ane F. Tapparo +5 more
doaj +1 more source
Rapid Spread of Novel Infectious Bursal Disease Virus Variant (Genotype A2dB1b) in the Near East and Persian Gulf Regions: Molecular Surveillance and Phylodynamic Reconstruction. [PDF]
Infectious bursal disease virus (IBDV) is one of the most impactful pathogens of poultry, with disease manifestations ranging from acute forms to subclinical but immunosuppressive infections. This heterogeneity, accompanied by a significant antigenic variability, is sustained by high mutation rates and frequent reassortments between the two genome ...
Poletto F +6 more
europepmc +2 more sources
Improvement of ibdv vp2 protein expression in escherichia coli through a staged ph control strategy [PDF]
Infectious bursal disease (IBD), caused by infectious bursal disease virus (IBDV), severely endangers the global poultry industry. The VP2 subunit vaccine represents a primary strategy for the prevention and control of IBD.
Qiang FU +7 more
doaj +1 more source
Isolation and genomic characteristics of the novel variant infectious bursal disease virus in China
The infectious bursal disease virus (IBDV) is a member of the viruses that can induce immunosuppression in chickens. In recent years, more and more IBDV-infected cases by the novel variant IBDV were reported in China, and it has been demonstrated that ...
Zongyi Bo +11 more
doaj +1 more source
First detection of natural co-infection with mutated very virulent IBDV (mvvIBDV) and novel variant IBDV (nVarIBDV). [PDF]
Infectious bursal disease (IBD), a globally important immunosuppressive disease of poultry caused by infectious bursal disease virus (IBDV), continues to pose a substantial threat to the poultry industry. For the past three decades, very virulent IBDV (vvIBDV), associated with high mortality, have been the predominant epidemic threat.
Yu H +16 more
europepmc +3 more sources
TRIM25 knockdown/knockout enhances IBDV replication.
(A-B) Validation of the optimal siRNA targeting TRIM25 by Western blotting (A) and RT-qPCR (B). (A) HEK293T cells were co-transfected with siRNAi (siTRIM25-1, siTRIM25-2, siTRIM25-3, and negative siRNA control siSc.) and pFlag-TRIM25, and the expression ...
Aijing Liu (662185) +21 more
core +1 more source
Development of diagnostic tools for IBDV detection using plants as bioreactors [PDF]
AbstractInfectious bursal disease virus (IBDV) is the etiological agent of an immunosuppressive and highly contagious disease that affects young birds, thus causing important economic losses in the poultry industry. Multimeric particles with different architectures based on the capsid protein VP2 have been widely produced for different purposes.
Evangelina Gómez +5 more
openaire +5 more sources
Molecular insights of recently circulated Infectious Bursal Disease Virus (IBDV) in broiler chicken in Egypt [PDF]
IBDV is still one of the most important causes of significant economic losses in poultry industry in Egypt, although implementation of the intensive vaccination programs.
Gabr El-Bagoury +3 more
doaj +1 more source
Pathogenesis and Host Response to A3B4 and A3B2 Infectious Bursal Disease Virus Strains in Chickens. [PDF]
Recently, the identification of novel reassortants of infectious bursal disease (IBD) virus (IBDV) was reported. Interestingly, these strains competed with the previously dominant A3B2 lineage, becoming the prevalent lineage in Poland and disseminating to other countries in Europe.
Pikuła A +3 more
europepmc +2 more sources
Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive avian disease caused by IBD virus (IBDV). Cell apoptosis triggered by IBDV contributes to the dysfunction of immune system in host.
Yao Qin +17 more
doaj +1 more source

