Results 1 to 10 of about 4,173 (212)

Modeling Infectious Bursal Disease Virus (IBDV) Antigenic Drift In Vitro. [PDF]

Viruses, 2022
Infectious bursal disease virus (IBDV) vaccines do not induce sterilizing immunity, and vaccinated birds can become infected with field strains. Vaccine-induced immune selection pressure drives the evolution of antigenic drift variants that accumulate amino acid changes in the hypervariable region (HVR) of the VP2 capsid, which may lead to vaccine ...
Asfor AS, Reddy VRAP, Nazki S, Urbaniec J, Brodrick AJ, Broadbent AJ.   +5 more
europepmc   +5 more sources

Flagellin Improves the Immune Response of an Infectious Bursal Disease Virus (IBDV) Subunit Vaccine. [PDF]

Vaccines (Basel), 2022
Flagellin activates the immune system through Toll-like receptor 5 (TLR5) and can work as an adjuvant for subunit vaccines. In this study, we tested the adjuvancy of two different N-terminal fragments of flagellin, (1) FliC99, residues 1–99, and (2) FliC176, residues 1–176, to incorporate larger areas of the hotspot region for potentially higher levels
Murtaza A, Afzal H, Doan TD, Ke GM, Cheng LT.   +4 more
europepmc   +4 more sources

A Preventive Cytokine Treatment of the Viral Infectious Bursal Disease (IBD) of Chickens [PDF]

The Journal of Poultry Science, 2015
Infectious bursal disease (IBD) is a viral disease of young chickens that produce severe lesions in the bursa of Fabricius and other organs inducing immunosuppression and mortality in birds.
Rosana Mattiello, Elisa D’Ambrosio, Maximiliano Wilda, Melisa Sayé, Mariana R. Miranda, Pablo Maure, Claudio A. Pereira, Fabio A. Digirolamo   +7 more
doaj   +3 more sources

Glycoprotein Production by Bursal Secretory Dendritic Cells in Normal, Vaccinated, and Infectious Bursal Disease Virus (IBDV)-Infected Chickens. [PDF]

Viruses, 2022
The aim of this study is to follow the gp production in IBDV-vaccinated and challenged birds. The progress of IBDV infection was monitored using anti-VP2 immunocytochemistry, light and transmission electron microscopy. In the medulla of the bursal follicle, the Movat pentachrome staining discovered an extracellular glycoprotein (gp) produced by bursal ...
Felföldi B, Benyeda Z, Kovács T, Nagy N, Magyar A, Oláh I.   +5 more
europepmc   +4 more sources

HSC70 is required for infectious bursal disease virus (IBDV) infection in DF-1 cells. [PDF]

Virol J, 2020
Abstract Background Infectious bursal disease (IBD) is a highly contagious infectious disease that causes severe immunosuppression and damage to the bursa of Fabricius in chickens. Several proteins involved in IBD virus (IBDV) infection, such as surface immunoglobulin M, integrin, annexin A2 and chicken heat shock protein 90, have been identified ...
Chen C, Qin Y, Qian K, Shao H, Ye J, Qin A.   +5 more
europepmc   +5 more sources

An Improved, Dual-Direction, Promoter-Driven, Reverse Genetics System for the Infectious Bursal Disease Virus (IBDV). [PDF]

Viruses, 2022
The infectious bursal disease virus (IBDV), one member of the Birnaviridae family, causes immunosuppression in young chickens by damaging the mature B cells of the bursa of Fabricius (BF), the central immune system of young chickens. The genome of IBDV is a bisegmented, double-strand RNA (dsRNA).
Hu X, Chen Z, Wu X, Ding Z, Zeng Q, Wu H.   +5 more
europepmc   +4 more sources

Infectious bursal disease virus (IBDV) as a novel oncolytic virotherapy in glioblastoma. [PDF]

J Immunother Cancer
Background Glioblastoma (GBM) is the most aggressive form of cancer of the central nervous system. Despite advances in immunotherapies and standard-of-care treatments for GBMs, clinical outcomes remain limited—owing to the immunosuppressive tumor microenvironment and the intrinsic resistance of GBM to ...
Tur-Planells V, Bykov Y, Dawodu G, García-Romero N, Izpura-Luis S, Pérez-Rodríguez L, Rius-Rocabert S, Palacín-Aliana I, Arranz-Herrero J, Márquez-Leiva I, Monago-Sanchez A, Del Rio ML, Rodriguez-Barbosa JI, Cano-Ochando J, García-Sastre A, Lozano-Ojalvo D, Nistal-Villan E, Ayuso-Sacido A, Cuadrado-Castano S.   +18 more
europepmc   +4 more sources

Prevalence of infectious bursal disease in chicken populations in China during 1983–2024: a meta-analysis [PDF]

Frontiers in Veterinary Science
ImportanceInfectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive disease caused by the Infectious bursal disease virus (IBDV), which has brought significant economic losses to China's chicken industry.
Mingfeng Chu, Junxue Qiu, Huiying Zhang, Shuiyun Chen, Yuchen Liang, Mengke Si, Yiwei Wang, Wei Cheng, Baolei Yang, Xiaoyu Chong, Xuelong Chen, Xuelong Chen, Yanping Qi, Yanping Qi   +13 more
doaj   +2 more sources

New oligonucleotide microarray for rapid diagnosis of avian viral diseases [PDF]

Virology Journal, 2017
Background We developed a new oligonucleotide microarray comprising 16 identical subarrays for simultaneous rapid detection of avian viruses: avian influenza virus (AIV), Newcastle disease virus (NDV), infection bronchitis virus (IBV), and infectious ...
Kulyaisan T. Sultankulova, Nurlan S. Kozhabergenov, Vitaliy M. Strochkov, Yerbol D. Burashev, Kamshat A. Shorayeva, Olga V. Chervyakova, Nurkuisa M. Rametov, Nurlan T. Sandybayev, Abylay R. Sansyzbay, Mukhit B. Orynbayev   +9 more
doaj   +2 more sources

Non-Lytic Egression of Infectious Bursal Disease Virus (IBDV) Particles from Infected Cells. [PDF]

PLoS One, 2017
Infectious bursal disease virus (IBDV), a member of the Birnaviridae family, is responsible for a devastating immunosuppressive disease affecting juvenile domestic chickens. IBDV particles are naked icosahedrons enclosing a bipartite double-stranded RNA genome harboring three open reading frames (ORF).
Méndez F, Romero N, Cubas LL, Delgui LR, Rodríguez D, Rodríguez JF.   +5 more
europepmc   +6 more sources