Results 41 to 50 of about 1,288 (185)
Fluconazole-Resistant Vulvovaginal Candidosis: An Update on Current Management [PDF]
PharmaceuticsCurrently, the rising prevalence of resistant Candida species, particularly Candida albicans, as well as non-albicans isolates such as Candida glabrata and Candida krusei, represent challenges in their management.
Karolina Akinosoglou +4 more
doaj +2 more sources
Invasive Pulmonary Aspergillosis in Non-Neutropenic Patients: An Evolving Clinical Paradigm [PDF]
DiagnosticsInvasive pulmonary aspergillosis (IPA), traditionally associated with severe immunosuppression and neutropenia, is increasingly reported among non-neutropenic patients.
Rocco Morena +3 more
doaj +2 more sources
Antifungal Agents in the 21st Century: Advances, Challenges, and Future Perspectives [PDF]
Infectious Disease ReportsInvasive fungal infections (IFIs) represent a growing global health threat, particularly for immunocompromised populations, with mortality exceeding 1.5 million deaths annually.
Francesco Branda +7 more
doaj +2 more sources
Health Science ReportsBackground and Aims Inconsequential diseases can sometimes become extremely dangerous through mutation. Antifungal resistance has increased by 24%, and resistance only due to Candida auris (C. auris) species have increased by 60%.
Md. Ashrafur Rahman +4 more
doaj +2 more sources
Promising antimycotics for the treatment of invasive infections [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 This paper provides a review of the largest studies (over the period of 2018 to 2023) of promising novel antimycotics and their possible role in the treatment of invasive mycoses, including infections caused by resistant Candida and Aspergillus isolates.
Ortenberg E.А.
doaj +1 more source
Profil ADME dari Entitas Molekul Baru yang Disetujui oleh FDA Tahun 2021: Suatu Kajian In Silico [PDF]
, 2022 Aspek farmakokinetik dan farmakodinamik yang diwakili oleh sifat adsorpsi, distribusi, metabolisme, ekskresi (ADME) merupakan syarat penting suatu obat dapat menuju targetnya.
Arief, Ihsanul, Hairunnisa, Hairunnisa
core +1 more source
The Latest FDA-Approved Pharmaceuticals Containing Fragments of Tailor-Made Amino Acids and Fluorine [PDF]
, 2022 Nowadays, the selective introduction of fluorine into bioactive compounds is a mature strategy in the design of drugs allowing to increase efficiency, biological half-life and bio-absorption. On the other hand, amino acids (AAs) represent one of the most
Butler, Greg +5 more
core +1 more source
Fungal cell wall : An underexploited target for antifungal therapies [PDF]
, 2021 Funding: The authors would like to acknowledge support from the University of Aberdeen and Abia State University. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Ibe, Chibuike, Munro, Carol
core +1 more source
Oral Ibrexafungerp: an investigational agent for the treatment of vulvovaginal candidiasis [PDF]
Expert Opinion on Investigational Drugs, 2020 Vulvovaginal candidiasis (VVC) is a common fungal infection caused by predominantly Candida albicans, and is diagnosed in up to 40% of women with vaginal complaints in the primary care setting. Approximately 75% of women experience at least one episode during their reproductive years.Ibrexafungerp is an orally active, semi-synthetic triterpenoid glucan
Nkechi, Azie +3 more
openaire +2 more sources
Journal of Fungi, 2023 The epidemiology of invasive fungal infections (IFIs) is currently changing, driven by aggressive immunosuppressive therapy, leading to an expanded spectrum of patients at risk of IFIs.
Roya Vahedi-Shahandashti +3 more
doaj +1 more source