Results 1 to 10 of about 848 (155)

Fosmanogepix for the Treatment of Invasive Mold Diseases Caused by Aspergillus Species and Rare Molds: A Phase 2, Open-Label Study (AEGIS). [PDF]

Clin Infect Dis
Abstract Background Fosmanogepix (FMGX) inhibits glycosylphosphatidylinositol anchored cell wall transfer protein 1, essential for anchoring mannoproteins to fungal cell wall, critical for host invasion. This Phase 2 study evaluated efficacy and safety of FMGX treatment in invasive mold diseases (IMDs)
Hodges MR, Tawadrous M, Cornely OA, Thompson GR, Slavin MA, Maertens JA, Dadwal SS, Rahav G, Hazel S, Almas M, Jakate A, Pypstra R.   +11 more
europepmc   +3 more sources

Action Mechanisms of Medicinal Plant Components as Antimycosis: A Literature Review [PDF]

Mycosis poses a significant threat to global health, particularly in immune-compromised individuals, and the rise of antifungal resistance has further complicated their treatment.
Abusalim, Ghadah S., Ashour, Ahmed, Balah, Mohamed A., El-Sakhawy, Mohamed A.   +3 more
core   +2 more sources

High-Risk Neutropenic Fever and Invasive Fungal Diseases in Patients with Hematological Malignancies [PDF]

Invasive fungal diseases (IFDs) still represent a relevant cause of mortality in patients affected by hematological malignancies, especially acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) undergoing remission induction chemotherapy, and
Acerbis A., Bernardi M., Castagna A., Chiurlo M., Ciceri F., Clerici D., Corti C., Diotallevi S., Farina F., Galli L., Greco R., Lolatto R., Lupo Stanghellini M. T., Mastaglio S., Mori G., Oltolini C., Peccatori J., Puoti M., Ripa M., Xue E.   +19 more
core   +1 more source

A one health roadmap towards understanding and mitigating emerging Fungal Antimicrobial Resistance: fAMR [PDF]

The emergence of fungal antimicrobial resistance-fAMR-is having a growing impact on human and animal health, and food security. This roadmap charts inter-related actions that will enhance our ability to mitigate the risk of fAMR.
Armstrong-James D, Bromley M, Burnett F, Chandler C, Fisher MC, Gow NAR, Gurr S, Hart A, Holmes A, May RC, Quinn J, Soliman T, Talbot NJ, West HM, West JS, White PL   +15 more
core  

Candida auris: an emerging antimicrobial-resistant organism with the highest level of concern

, 2023
Mishra Baishnab, Shyam Kumar , Mishra, SK, Willcox, M , Yasir, M   +3 more
core   +1 more source

Incontinentia pigmenti – case report [PDF]

Introducere Incontinentia pigmenti (IP) este o genodermatoză rară, X-lincată, dominantă, cauzată de o mutație în gena IKBKG, care activează NF-kB, un factor de transcripție implicat în reacțiile imune și inflamatorii, creșterea și apoptoza celulară ...
Balmuș, Dorin, Beţiu, Mircea, Emeţ, Iulia, Rubanovici, Dumitru, Sturza, Vasile   +4 more
core  

Multisystem <i>Lomentospora prolificans</i> progression on fosmanogepix despite <i>in vitro</i> activity: a call for expanding clinical research on novel antifungals. [PDF]

ASM Case Rep
Cooper RA, Arif S, Baker AW, Wiederhold NP, Sarantopoulos S, Iftikhar M, Stanly K, Collis B, Ni B, Sim BZ, Perfect JR, Alexander BD, Heldman MR.   +12 more
europepmc   +1 more source

Fungal Meningitis in US Patients Who Received Epidural Anesthesia in Matamoros, Mexico. [PDF]

Clin Infect Dis
Smith DJ, Misas E, Gold JAW, Evert N, Dang T, Prot E, Godwin S, Rivas J, Pearson J, Koenecke L, Bustamante ND, Marinissen MJ, Rodriquez GG, López-Martínez I, Lutfy C, Williams S, Vazquez Deida AA, Byrd KM, Villalba JA, Reagan-Steiner S, Parnell L, Gade L, Humphries RM, Wiederhold NP, Chiu CY, Lieberman JA, Litvintseva AP, Chiller T, Ostrosky-Zeichner L, Fungal Meningitis Response Team.   +29 more
europepmc   +1 more source

The Four Critical Priority Fungi According to the World Health Organization and the Hope for New Therapies: A Focus on Cell Wall Antifungal Targets. [PDF]

J Fungi (Basel)
Marena GD, Carvalho GC, Magalhães MHC, Figueiredo JM, Ramos DH, Nosanchuk JD, Taborda CP.   +6 more
europepmc   +1 more source

Disseminated Fungal Infection in Profoundly Immunocompromised Hosts: A Three-Case Series. [PDF]

Cureus
Wang A, Greene J.
europepmc   +1 more source