Results 81 to 90 of about 27,849,568 (325)

Berberine improves intestinal epithelial tight junctions by upregulating A20 expression in IBS-D mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
To investigate effects of berberine exerts on A20 expression and regulation of intestinal epithelial tight junctions via the TNF-α-NF-κB-MLCK pathway in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D). C57BL/6 wild type (WT) and A20 IEC-KO mice (48
Qiu-Ke Hou, Shui-lian Zhu, Chang-rong Zhang, Yong-quan Huang, Yajuan Guo, Pei-Wu Li, Xinlin Chen, Yi Wen, Quan‐Bing Han, Fengbin Liu   +9 more
semanticscholar   +1 more source

Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2

Advanced Science, EarlyView.
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim, Wonjae Ko, Byoung‐Hoon Lee, Sanghoon Kim, Yun Do Kim, Hyunsoo Ahn, Yoon Jung, Chan Woo Lee, Kug‐Seung Lee, Eunhee Gong, Junho Lee, Minho Kim, Taeghwan Hyeon, Su‐Il In   +13 more
wiley   +1 more source

From Discomfort to Delight: Diet's Impact on IBS-D

Journal of Clinical Medical Research, 2023
Duke University was founded in 1930 primarily due to funds generated from James B Duke’s tobacco business. Duke achieved great financial wealth primarily due to the early application of machine rolled cigarettes, as opposed to hand rolled. This early adoption of technology allowed Duke Tobacco to out-produce other companies still selling hand rolled ...
openaire   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Efficacy of Tong-Xie-Yao-Fang granule and its impact on whole transcriptome profiling in diarrhea-predominant irritable bowel syndrome patients: study protocol for a randomized controlled trial

Trials, 2020
Background Irritable bowel syndrome (IBS) is one kind of common functional bowel disease with obscure pathogenesis, and exploration about whole transcriptome profiling in IBS-D is still negligible.
Yan Wang, Yong-quan Huang, Shui-lian Zhu, Chang-rong Zhang, Xin-lin Chen, Qiu-ke Hou, Feng-bin Liu   +6 more
doaj   +1 more source

The Chinese herbal formula Huoxiang Zhengqi for diarrhea-predominant irritable bowel syndrome (CHAIRS): a study protocol for a double-blinded randomized controlled trial

Trials, 2021
Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common chronic digestive disease. Recent observational studies have reported that the Chinese herbal formula Huoxiang Zhengqi (HXZQ) can relieve IBS-D symptoms, but no high-level ...
Xiaohui Guo, Meiling Xuan, Huan Zheng, Shumin Qin, Haomeng Wu, Shaogang Huang, Zehuai Wen   +6 more
doaj   +1 more source

NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes

Advanced Science, EarlyView.
Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang, Jaehun Kim, Sungwoo Hong   +2 more
wiley   +1 more source

Synergistic NiO‐NiCo Heterostructure Electrode for Highly Active and Durable Hydrogen Evolution in Industrial Alkaline Water Electrolysis

Advanced Science, EarlyView.
This study presents a NiO–NiCo heterostructure electrode that enhances water dissociation and hydrogen adsorption through synergistic interfacial interactions, verified by electrochemical and spectroscopic analyses. Its high performance in a large‐area single‐cell system under dynamic conditions demonstrates how rational non‐precious catalyst design ...
Jinwoo Lee, Kyungbeen Yeom, Gaeun Hong, Yoojin Shin, Ji Seong Hyoung, Ji Eun Park, Heonjoong Lee, Taeyang Han, Yung‐Eun Sung, Jeong Won Kang, Kyoung‐Soo Kang, Hyunjoon Lee   +11 more
wiley   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Network pharmacology and experimental validation to explore the mechanism of Changji'an formula against irritable bowel syndrome with predominant diarrhea

Heliyon
Changji'an Formula (CJAF) is a Chinese herbal compound, which is effective against irritable bowel syndrome with predominant diarrhea (IBS-D) in clinic. However, the molecular mechanism has not been well defined.
Wei Ke, Jinjun Wu, Hongbin Li, Siyu Huang, Huibiao Li, Yongfu Wang, Yingxiu Wu, Jie Yuan, Shuncong Zhang, Hongmei Tang, Kaijun Lei   +10 more
doaj   +1 more source