Results 191 to 200 of about 80,333 (276)

Comparing Ibuprofen and Loop Diuretics for Protein-Bound Uremic Toxins Clearance During Hemodialysis. [PDF]

Kidney Int Rep
Escudero-Saiz VJ, Cuadrado-Payán E, Rodríguez-García M, Casals G, Rodas LM, Fontseré N, Salgado MDC, Bastida C, Rico N, Broseta JJ, Maduell F.   +10 more
europepmc   +1 more source

Evaluating the Impact of Outcome Delay on the Efficiency of Sample Size Re‐Estimation

Pharmaceutical Statistics, Volume 25, Issue 6, November/December 2026.
ABSTRACT Sample size re‐estimation (SSR) can be a powerful tool to ensure that a clinical trial meets its pre‐specified power requirements when uncertainty regarding a design parameter exists at the planning stage. However, long‐term primary endpoints can be harmful to the efficiency of this trial design.
Aritra Mukherjee, Michael J. Grayling, James M. S. Wason   +2 more
wiley   +1 more source

Development of a Biphasic Modified-Release Ibuprofen Tablet Formulation: Single-Dose and Multiple-Dose Pharmacokinetics and Food-Effect Studies. [PDF]

Clin Transl Sci
Kvapilová L, Hofmann J, Černý J, Hauser T, Bouhajib M, Šíma M, Slanař O.   +6 more
europepmc   +1 more source

Shaping Development Through Parents: A Scalable Approach to Early Learning

Developmental Science, Volume 29, Issue 6, November 2026.
ABSTRACT Early childhood is a sensitive period for cognitive, language, and socio‐emotional development, with parental engagement playing a central role. In Argentina, families facing socioeconomic adversity often encounter barriers that limit access to developmentally enriching parent–child activities; heightening developmental risk amid ongoing ...
Gonzalez‐Gomez Nayeli, Naso Cecilia Eugenia, Tierney Fiona, Soba Roxana, Vazquez Claudia, Hendry Alexandra   +5 more
wiley   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Chemical tailoring of CQD/PEDOT hybrid materials with silver, molybdenum, and iridium for ibuprofen sensing: a computational approach. [PDF]

RSC Adv
Abubakar MN, Ebereonwu PU, Okon GA, Folorunso TR, Tillo MK.   +4 more
europepmc   +1 more source

Microparticles Based on Chitosan/Xanthan Gum Polyelectrolyte Complex Modulate the Anti-Inflammatory and Antinociceptive Effects of Ibuprofen and Escin. [PDF]

Mar Drugs
Ćirić A, Martić N, Bosanac M, Andrejić Višnjić B, Rašković A, Đekić L.   +5 more
europepmc   +1 more source

Essential, Yet Precarious, Mistreated, Sick and Medicalized: A Sequential Explanatory Mixed‐Methods Study on Homecare Aides in Spain

American Journal of Industrial Medicine, Volume 69, Issue 10, Page 814-829, October 2026.
ABSTRACT Background Homecare aides (HCAs) are professional non‐family caregivers, who support dependent individuals to live at home with dignity; yet in Spain they remain understudied and vulnerable, often facing precarious working conditions. We aimed to characterize HCAs’ employment, living conditions, health, and exposure to workplace violence and ...
Albert Navarro‐Giné, Pedro Ferrer‐Rosende, Maria Feijoo‐Cid, Sergio Salas‐Nicás, Laura Esteve‐Matalí, Valeria Stuardo‐Ávila, María Isabel Fernández‐Cano   +6 more
wiley   +1 more source

The Role of Surface Chemistry and pH Shifts in the Sorption of Common NSAIDs on Coconut and Orange Waste-Derived Carbon Materials. [PDF]

Molecules
Olivarez JA, Hernández V, Mandujano-Zúñiga HP, Sánchez RA, Godínez LA, García-Espinoza JD, Vela-Carrillo AZ, Rodríguez-Valadez FJ, Santos-Blanco M, Ortega-Borges R, Robles I.   +10 more
europepmc   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source