From Hydrogen Bonding to Hydrophobic Control: The Shifting Solvation Mechanism of Ibuprofen in Deep Eutectic Solvents. [PDF]
Piccoli V, Pádua A, Martínez L.
europepmc +1 more source
Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud +4 more
wiley +1 more source
In vitro ibuprofen has gene regulatory and anti-inflammatory properties in peripheral blood mononuclear cells of individuals with infection-provoked neurodevelopmental disorders. [PDF]
Han VX +10 more
europepmc +1 more source
Safety of Nonsteroidal Anti‐Inflammatory Drug Use in Traumatic Brain Injury
ABSTRACT Background Use of nonsteroidal anti‐inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14 days of TBI was associated with a clinically significant progression of intracranial bleed (PIB).
Jennifer Beavers +10 more
wiley +1 more source
Isolated Allergic Conjunctivitis Induced by an Oral Nonsteroidal Anti-inflammatory Drug (NSAID), Confirmed by an Oral Provocation Test: A Case Report. [PDF]
Hidan Y, Chafi J.
europepmc +1 more source
Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley +1 more source
In vitro evaluation of anti-inflammatory drugs Ibuprofen and Dexamethasone against Acinetobacter baumannii. [PDF]
Pakdel Z, Beikzadeh B.
europepmc +1 more source
Topical Analgesic Therapies for Acute, Sports-Associated Soft Tissue Injuries. [PDF]
Howard MS, Lee-Smith W, Reinert JP.
europepmc +1 more source
Comparison of Metrics for Investigating Bioequivalence in Onset of Action in Incurred Bioequivalence Studies. [PDF]
Paixao P +7 more
europepmc +1 more source

