Results 211 to 220 of about 80,333 (276)

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

open access: yesPediatric Anesthesia, Volume 36, Issue 10, Page 1308-1315, October 2026.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud   +4 more
wiley   +1 more source

In vitro ibuprofen has gene regulatory and anti-inflammatory properties in peripheral blood mononuclear cells of individuals with infection-provoked neurodevelopmental disorders. [PDF]

open access: yesInflammopharmacology
Han VX   +10 more
europepmc   +1 more source

Safety of Nonsteroidal Anti‐Inflammatory Drug Use in Traumatic Brain Injury

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 10, October 2026.
ABSTRACT Background Use of nonsteroidal anti‐inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14 days of TBI was associated with a clinically significant progression of intracranial bleed (PIB).
Jennifer Beavers   +10 more
wiley   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

open access: yes
Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
Suna Lin   +6 more
wiley   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Comparison of Metrics for Investigating Bioequivalence in Onset of Action in Incurred Bioequivalence Studies. [PDF]

open access: yesPharmaceutics
Paixao P   +7 more
europepmc   +1 more source

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