Results 221 to 230 of about 80,333 (276)

Ge-Gen Decoction Modulates the HSP90/AKT Signaling Pathway and the NLRP3 Inflammasome to Alleviate Primary Dysmenorrhea. [PDF]

J Pain Res
Xie Y, Xu L, He Y.
europepmc   +1 more source

Self-Poisoning With Ibuprofen in Youth: A What, When and Why Clinical Framework. [PDF]

Clin Med Insights Pediatr
Dehestani B, Kelly L, McNicholas F.
europepmc   +1 more source

Electrochemical Synthesis of Building Blocks with a Structure Inspired by Nonsteroidal Anti-Inflammatory Drugs. [PDF]

ACS Omega
Adamek J, Październiok-Holewa A.
europepmc   +1 more source

Sila-Ibuprofen [PDF]

Journal of Medicinal Chemistry, 2020
The synthesis, characterization, biological activity, and toxicology of sila-ibuprofen, a silicon derivative of the most common nonsteroidal anti-inflammatory drug, is reported. The key improvements compared with ibuprofen are a four times higher solubility in physiological media and a lower melting enthalpy, which are attributed to the carbon-silicon ...
Florian Kleemiss, Aileen Justies, Daniel Duvinage, Patrick Watermann, Eric Ehrke, Kunihisa Sugimoto, Malte Fugel, Lorraine A. Malaspina, Anneke Dittmer, Torsten Kleemiss, Pim Puylaert, Nelly R. King, Anne Staubitz, Thomas M. Tzschentke, Ralf Dringen, Simon Grabowsky, Jens Beckmann   +16 more
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Ibuprofen in Osteoarthritis

Southern Medical Journal, 1977
In a double-blind, multiclinic study, 437 patients with osteoarthritis were treated sequentially with ibuprofen, 1,800 mg/day, and placebo, or with aspirin, 3,600 mg/day, and placebo. Each treatment was given for four weeks. Considering relief of pain, ability to function, and general well-being, the patients preferred drug to placebo, usually by a ...
J E, Giansiracusa, M S, Donaldson, M L, Koonce, T E, Lefton, G E, Ruoff, C D, Brooks   +5 more
openaire   +2 more sources

The Metabolism of Ibuprofen

Xenobiotica, 1973
1. After oral administration ibuprofen appeared mainly in unchanged form in the plasma of rats, dogs, baboons and men.
R F, Mills, S S, Adams, E E, Cliffe, W, Dickinson, J S, Nicholson   +4 more
openaire   +2 more sources

Pharmacokinetics of Ibuprofen

The American Journal of Medicine, 1984
The pharmacokinetics of ibuprofen (Motrin) are best described by a two-compartment open model. Ibuprofen pharmacokinetics are only minimally influenced by advanced age, the presence of alcoholic liver disease, or rheumatoid arthritis. Levels of ibuprofen in breast milk are negligible.
K S, Albert, C M, Gernaat
openaire   +2 more sources