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Pharmacokinetics of ibuprofen: comparison of the fixed combination of ibuprofen plus caffeine with ibuprofen lysinate or ibuprofen acid

Evidence for Self-Medication, 2021
Analgesics containing readily soluble ibuprofen (e.g. as the lysinate) were developed with the aim of ensuring a more rapid relief of pain than ibuprofen acid through faster absorption in the gastrointestinal tract. Since the degree of gastric filling can have a significant influence on absorption, two studies investigated the pharmacokinetics of ...
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Ibuprofen

Annals of Internal Medicine, 1979
Ibuprofen was introduced in England in 1967 and in the United States in 1974 as an anti-inflammatory drug in humans. It has weak but definite anti-inflammatory properties similar to those of aspirin, milligram for milligram, but with considerably less adverse effect on the stomach. Ibuprofen is chemically related to fenoprofen and naproxen, but lack of
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Ibuprofen for Fever

Pediatrics, 1991
To the Editor.— I am writing to voice concern about the use of ibuprofen for simple antipyresis in infants and young children. Although there have been enough data about the new liquid preparation to convince the Federal Drug Administration to release it, it must be recognized that the total number of infants and young children reported ...
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Ibuprofen and Dysmenorrhea

The American Journal of Medicine, 1984
Primary dysmenorrhea and secondary dysmenorrhea induced by an intrauterine device are associated with increased production and release of endometrial prostaglandins. The condition may be treated by oral contraceptives, which reduce overall menstrual fluid volume, or by a prostaglandin synthetase inhibitor, such as ibuprofen.
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Comparative Pharmacology of S(+)-Ibuprofen and (RS)-Ibuprofen

Clinical Rheumatology, 2001
Racemic ibuprofen, which contains equal quantities of R(-)-ibuprofen and S(+)-ibuprofen, has been used as an anti-inflammatory and analgesic agent for over 30 years. Although the S(+)-enantiomer is capable of inhibiting cyclooxygenase (COX) at clinically relevant concentrations, R(-)-ibuprofen is not a COX inhibitor.
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Ibuprofen

American Pharmacy, 1985
D A, Hussar, N A, Hodge
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Ibuprofen see Indomethacin/ibuprofen

Reactions Weekly, 1990
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