Nonsteroidal Anti-Inflammatory Drugs and Ectodomain Shedding of the Amyloid Precursor Protein [PDF]
Background: Epidemiological studies have suggested that long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of Alzheimer's disease (AD).
Czirr, Eva+8 more
core +1 more source
Ibuprofen is one of the NSAID (NonSteroid Anti Inflamation Drug) drugs that has been widely used as antipyretic agent, analgesic dan anti-inflamation. Vitamin C is an important nutrient for the body and has been widely used to maintain health.
Sattrio Desrianto Prabowo+2 more
doaj +1 more source
Bioavailability of ibuprofen following oral administration of standard ibuprofen, sodium ibuprofen or ibuprofen acid incorporating poloxamer in healthy volunteers [PDF]
Abstract Background The aim of this study was to compare the pharmacokinetic properties of sodium ibuprofen and ibuprofen acid incorporating poloxamer with standard ibuprofen acid tablets. Methods Twenty-two healthy volunteers were enrolled into this randomised, single ...
Peter M. Dewland+2 more
openaire +3 more sources
Ibuprofen disappeared from the pharmacy shelves during the 2019 coronavirus (COVID-19) pandemic. However, a while later, information circulated that ibuprofen should be avoided as it could worsen COVID-19 symptoms.
L. A. Abu Esba+5 more
semanticscholar +1 more source
EFEK ULCEROGENIC DISPERSI PADAT IBUPROFEN-POLIVINILPIROLIDON (PVP) PADA TIKUS PUTIH JANTAN
Ibuprofen is an anti inflammatory, analgesic, and antipyretic agent. It has low solubility and bioavailability. The administration of ibuprofen in a long time and high dose can increased of side effect at gastrointestinal (peptic ulcer). This study was
Ririt Vita Febrianti , Iis Wahyuningsih
doaj +1 more source
Continuous Melt Granulation for Taste-Masking of Ibuprofen
Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
doaj +1 more source
The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl [PDF]
The cogrinding technique is one of most effective methods for improving the dissolution of poorly water-soluble drugs and it is superior to other approaches from an economical as well as an environmental standpoint, as the technique does not require any ...
Ali Nokhodchi+8 more
core +1 more source
Effect of Nonintervention vs Oral Ibuprofen in Patent Ductus Arteriosus in Preterm Infants
Key Points Question Is the nonintervention approach noninferior to oral ibuprofen treatment for hemodynamically significant patent ductus arteriosus with ductal size greater than 1.5 mm plus assisted respiratory support in very preterm infants?
S. Sung+4 more
semanticscholar +1 more source
Controlled release properties and final macroporosity of a pectin microspheres–calcium phosphate composite bone cement [PDF]
The use of calcium phosphate cements (CPC) is restricted by their lack of macroporosity and poor drug release properties. To overcome these two limitations, incorporating degradable polymer microparticles into CPC is an attractive option, as polymer ...
Freche, Michèle+4 more
core +1 more source
Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis [PDF]
The use of cyclo-oxygenase 2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased risk of acute myocardial infarction (AMI). The association between the risks of AMI with nonselective NSAIDs is less clear.
Langhorne, P.+3 more
core +2 more sources