Results 21 to 30 of about 53,379 (247)

Serious infectious events and ibuprofen administration in pediatrics: a narrative review in the era of COVID-19 pandemic

Italian Journal of Pediatrics, 2021
Purpose of review Despite its recognized efficacy and tolerability profile, during the last decade a rise of adverse events following ibuprofen administration in children has been reported, including a possible role in worsening the clinical course of ...
Lucia Quaglietta, Massimo Martinelli, Annamaria Staiano   +2 more
doaj   +1 more source

Efficacy and Long-Term Safety of Ibuprofen Gargle for Oral Lichen Planus: A Study Protocol of Randomized Crossover and Long-Term Extension Trials

Methods and Protocols, 2023
Oral lichen planus (OLP) is a type of chronic and refractory stomatitis characterized by abnormal keratinization, which is often painful. There is no consensus regarding treatment options for OLP, particularly in the presence of pain.
Yumi Kitahiro, Takeshi Ioroi, Yasumasa Kakei, Junya Yamashita, Akira Kimoto, Takumi Hasegawa, Asami Morioka, Kazuhiro Yamamoto, Masaya Akashi, Ikuko Yano   +9 more
doaj   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Comparative study of anti-inflammatory, ulcerogenic and cytotoxic activities of racemate and S-ibuprofen

Revista de Ciências Farmacêuticas Básica e Aplicada, 2013
Ibuprofen is widely commercialized in racemic form. Although metabolic chiral inversion occurs through the conversion of R(-)-ibuprofen to S(+)-ibuprofen and the latter enantiomer is considered the active form, clinical trials involving the ...
Flavio Henrique Nuevo Benez, Caroline Candida de Oliveira, Simone Coghetto Acedo, Erica Martins Ferreira Gotardo, Lara Ester Câmara, Silvana Calafatti, Patricia de Oliveira Carvalho, Alessandra Gambero   +7 more
doaj   +2 more sources

Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment

Frontiers in Pediatrics, 2022
IntroductionIbuprofen is one of the most common non-steroidal anti-inflammatory drugs used to close patent ductus arteriosus (PDA) in preterm infants. PDA is associated with bronchopulmonary dysplasia (BPD), while PDA closure by ibuprofen did not reduce ...
Xuemei Huang, Xuemei Huang, Dongshan Han, Yanfei Wei, Bingchun Lin, Dingyuan Zeng, Dingyuan Zeng, Yu Zhang, Yu Zhang, Ba Wei, Zhifeng Huang, Xueyu Chen, Chuanzhong Yang   +12 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Ibuprofen as an Emerging Contaminant of Concern: Occurrence in Southeast Asia Water Environment [PDF]

E3S Web of Conferences
Ibuprofen is the third most salable pharmaceutical worldwide even being sold in the absence of prescription. This drug is not thoroughly metabolized and excreted into wastewater as an unchanged molecule and its metabolites.
Trianda Yenni, Adityosulindro Sandyanto, Moersidik Setyo Sarwanto   +2 more
doaj   +1 more source

Porous Hybrid Soft Actuators From Liquid Crystal Networks and Lyotropic Chromonic Liquid Crystal Templated Hydrogels

Advanced Materials, EarlyView.
The graphic illustrates the design of a hybrid bilayer composed of a liquid crystal hydrogel (LCH) and a liquid crystal network (LCN). The figure highlights the magnetic alignment of the chromonic hydrogel and the thermal‐responsive actuation of the LCN along with the LCH when both layers are aligned or misaligned, enabling programmable, light‐driven ...
Ramón Santiago Herrera Restrepo, Irving Hafed Tejedor García, Matthew Gene Scarfo, Negin Bouzari, Negar Rajabi, Olga Bantysh, Joel Torres‐Andrés, Christopher W. V. James, Maria Guix, Amirreza Aghakhani, Jordi Ignés‐Mullol, Salvador Pané, Josep Puigmartí‐Luis, Hamed Shahsavan   +13 more
wiley   +1 more source

Ibuprofen: Synthesis, production and properties [PDF]

Hemijska Industrija, 2003
Since its introduction in 1969, ibuprofen has become one of the most common painkillers in the world. Ibuprofen in an NSAID (non-steroidal anti-inflammatory drug) and like other drugs of its class it possesses analgetic, antipyretic and anti-inflammatory
Mijin Dušan Ž., Stanković Milena, Petrović Slobodan D.   +2 more
doaj   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source