Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen.
PLoS ONE, 2021 The article expands our knowledge on the variety of biodegraders of ibuprofen, one of the most frequently detected non-steroidal anti-inflammatory drugs in the environment.
Irina B Ivshina +3 more
doaj +2 more sources
Controlled release ibuprofen-poloxamer gel for epidural use - A pharmacokinetic study using microdialysis in pigs [PDF]
, 2016 In order to avoid the risks of sideeffects of epidural local anesthetics and opioids, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) epidurally would be an interesting option of analgesic therapy. The fairly short duration of action of spinally
Bernards, Christopher M. +2 more
core +1 more source
Uji Drug Loading Ibuprofen Pada Material UiO-66 (Zr-Metal Organic Framework)
Jurnal Kimia Riset, 2019 Tujuan dari penelitian ini adalah untuk mengetahui nilai loading ibuprofen pada material UiO-66 (Zr-Metal Organic Framework). Pada penelitian ini, dilakukan variasi lama perendaman 12, 24, 36, 48, 60 dan 72 jam, sehingga didapatkan nilai drug loading ...
Tri Ana Mulyati, Fery Eko Pujiono
doaj +1 more source
Synthesis of Spin-Labeled Ibuprofen and Its Interaction with Lipid Membranes
Molecules, 2022 Ibuprofen is a non-steroidal anti-inflammatory drug possessing analgesic and antipyretic activity. Electron paramagnetic resonance (EPR) spectroscopy could be applied to study its interaction with biological membranes and proteins if its spin-labeled ...
Denis S. Baranov +2 more
doaj +1 more source
Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis [PDF]
, 2006 The use of cyclo-oxygenase 2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased risk of acute myocardial infarction (AMI). The association between the risks of AMI with nonselective NSAIDs is less clear.
Langhorne, P. +3 more
core +2 more sources
Molecules, 2012 A novel application of whole cells of Nocardia corallina B-276 for the deracemisation of ibuprofen is reported. This microorganism successfully hydrolysed ibuprofen nitrile to ibuprofen amide, and ibuprofen amide to ibuprofen, using a suspension of cells
Myrna Solís-Oba +4 more
doaj +1 more source
Journal of International Medical Research, 2019 Objective To determine whether 3% w/w levomenthol added to ibuprofen gel (5% w/w) improves its efficacy compared with ibuprofen gel alone or diclofenac gel (1.16%) for the treatment of soft-tissue injuries. Methods A total of 182 patients with acute soft-
Alan G. Wade +4 more
doaj +1 more source
Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen. [PDF]
, 2020 Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal,
Gomes, Aldrin V +5 more
core
In vivo metabolism of ibuprofen in growing conventional pigs : a pharmacokinetic approach [PDF]
, 2019 The juvenile conventional pig has been suggested as a preclinical animal model to evaluate pharmacokinetic (PK), pharmacodynamic (PD), and safety parameters in children. However, a lot of developmental changes in pig physiology still need to be unraveled.
Croubels, Siska +3 more
core +1 more source
Transcriptomic effects of the non-steroidal anti-inflammatory drug Ibuprofen in the marine bivalve Mytilus galloprovincialis Lam [PDF]
, 2016 The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L-1) are presented. Using a 1.7 K feature cDNA microarray along with linear models
Amorim, Monica J. B. +3 more
core +1 more source