Results 41 to 50 of about 167,791 (394)

Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years

JAMA Network Open, 2020
Key Points Question Are there differences in the antipyretic, analgesic, and safety profiles of acetaminophen (paracetamol) compared with ibuprofen for the short-term treatment of fever or pain in children younger than 2 years?
Eunicia Tan, I. Braithwaite, C. McKinlay, S. Dalziel   +3 more
semanticscholar   +1 more source

Comparison of diclofenac gel, ibuprofen gel, and ibuprofen gel with levomenthol for the topical treatment of pain associated with musculoskeletal injuries

Journal of International Medical Research, 2019
Objective To determine whether 3% w/w levomenthol added to ibuprofen gel (5% w/w) improves its efficacy compared with ibuprofen gel alone or diclofenac gel (1.16%) for the treatment of soft-tissue injuries. Methods A total of 182 patients with acute soft-
Alan G. Wade, Gordon M. Crawford, David Young, Stephen Corson, Colin Brown   +4 more
doaj   +1 more source

Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen. [PDF]

, 2020
Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal,
Gomes, Aldrin V, Mishra, Manish, Newens, Joanne L, Phinney, Brett S, Salemi, Michelle R, Tiwari, Shuchita   +5 more
core  

The influence of the preparation methods on the inclusion of model drugs in a β-cyclodextrin cavity [PDF]

, 2008
NOTICE: this is the author’s version of a work that was accepted for publication in European Journal of Pharmaceutics and Biopharmaceutics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting ...
Cassela, Charoenchaitrakool, Duan, Faucci, Fini, G. Feio, Gavira, Ghorab, Ghorab, H.M. Cabral Marques, Higgins, Higuchi, Hussein, J.F. Pinto, J.L. Figueirinhas, Jambhekar, Koester, Leite Pinto, Loftsson, Loftsson, Loftsson, Loftsson, Loftsson, Lu, Miller, Mura, Másson, Nerurkar, Oh, O’Brien, P.J. Salústio, Pose-Vilarnovo, Salvatierra, Scheneider, Silverstein, Sun, Tozuka, van Hees, Waleczek, Wu, Wulff   +40 more
core   +1 more source

Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2019
Importance Multimodal postoperative analgesia is widely used but lacks evidence of benefit. Objective Investigate beneficial and harmful effects of 4 nonopioid analgesics regimens. Design, Setting, and Participants Randomized, blinded, placebo-controlled,
K. Thybo, Daniel Hägi‐Pedersen, J. Dahl, J. Wetterslev, Mariam Nersesjan, J. Jakobsen, N. Pedersen, S. Overgaard, H. Schrøder, Harald Schmidt, Jan Gottfrid Bjørck, Kamilla Skovmand, R. Frederiksen, Morten Buus-Nielsen, C. V. Sørensen, L. S. Kruuse, P. Lindholm, O. Mathiesen   +17 more
semanticscholar   +1 more source

A renewable, sustainable and low-cost adsorbent for ibuprofen removal.

Water Science and Technology, 2020
Adsorption efficiency of acid-modified kola nut husk (KNHA) as a non-conventional adsorbent for the sorption of Ibuprofen from aqueous media was investigated in this study.
O. Bello, O. Alao, Temitope Chris Alagbada, Oluwatobi Samuel Agboola, Omotoyosi Toheeb Omotoba, Oluwatosin Rebecca Abikoye   +5 more
semanticscholar   +1 more source

Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen

New England Journal of Medicine
Background The cyclooxygenase inhibitor ibuprofen may be used to treat a patent ductus arteriosus (PDA) in preterm infants. We hypothesized that selective early treatment of large PDAs with ibuprofen would improve short-term outcomes.
Samir Gupta, N. Subhedar, J. L. Bell, D. Field, U. Bowler, E. Hutchison, Sam Johnson, W. Kelsall, J. Pepperell, T. Roberts, S. Sinha, K. Stanbury, J. Wyllie, Pollyanna Hardy, E. Juszczak   +14 more
semanticscholar   +1 more source

Controlled release ibuprofen-poloxamer gel for epidural use - A pharmacokinetic study using microdialysis in pigs [PDF]

, 2016
In order to avoid the risks of sideeffects of epidural local anesthetics and opioids, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) epidurally would be an interesting option of analgesic therapy. The fairly short duration of action of spinally
Bernards, Christopher M., Paavola, Anne, Rosenberg, Per H.   +2 more
core   +1 more source

Enzymatic Hydrolytic Resolution of Racemic Ibuprofen Ethyl Ester Using an Ionic Liquid as Cosolvent

Molecules, 2016
The aim of this study was to develop an ionic liquid (IL) system for the enzymatic resolution of racemic ibuprofen ethyl ester to produce (S)-ibuprofen. Nineteen ILs were selected for use in buffer systems to investigate the effects of ILs as cosolvents ...
Tao Wei, Kunpeng Yang, Bing Bai, Jie Zang, Xuan Yu, Duobin Mao   +5 more
doaj   +1 more source

The Intestinal and Biliary Metabolites of Ibuprofen in the Rat with Experimental Hyperglycemia

Molecules, 2022
Hyperglycemia is reported to be associated with oxidative stress. It can result in changes in the activities of drug-metabolizing enzymes and membrane-integrated transporters, which can modify the fate of drugs and other xenobiotics; furthermore, it can ...
Hawsar Othman Mohammed, Attila Almási, Szilárd Molnár, Pál Perjési   +3 more
doaj   +1 more source