Results 41 to 50 of about 142,129 (337)

Comparative study of anti-inflammatory, ulcerogenic and cytotoxic activities of racemate and S-ibuprofen

Revista de Ciências Farmacêuticas Básica e Aplicada, 2013
Ibuprofen is widely commercialized in racemic form. Although metabolic chiral inversion occurs through the conversion of R(-)-ibuprofen to S(+)-ibuprofen and the latter enantiomer is considered the active form, clinical trials involving the ...
Flavio Henrique Nuevo Benez, Caroline Candida de Oliveira, Simone Coghetto Acedo, Erica Martins Ferreira Gotardo, Lara Ester Câmara, Silvana Calafatti, Patricia de Oliveira Carvalho, Alessandra Gambero   +7 more
doaj   +2 more sources

Efficacy and Long-Term Safety of Ibuprofen Gargle for Oral Lichen Planus: A Study Protocol of Randomized Crossover and Long-Term Extension Trials

Methods and Protocols, 2023
Oral lichen planus (OLP) is a type of chronic and refractory stomatitis characterized by abnormal keratinization, which is often painful. There is no consensus regarding treatment options for OLP, particularly in the presence of pain.
Yumi Kitahiro, Takeshi Ioroi, Yasumasa Kakei, Junya Yamashita, Akira Kimoto, Takumi Hasegawa, Asami Morioka, Kazuhiro Yamamoto, Masaya Akashi, Ikuko Yano   +9 more
doaj   +1 more source

Gabapentin for pain management after osmotic dilator insertion and prior to dilation and evacuation: A randomized controlled trial. [PDF]

, 2020
ObjectiveTo evaluate if gabapentin 600 mg reduces pain after osmotic dilator placement the day before a dilation and evacuation (D&E) procedure.Study designWe conducted a double-blind, placebo-controlled, randomized (stratified by vaginal parity ...
Chen, Melissa J, Creinin, Mitchell D, Hou, Melody Y, Matulich, Melissa C, Melo, Juliana, Schimmoeller, Natasha R   +5 more
core   +3 more sources

Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries [PDF]

, 2013
PMCID: PMC3570554This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Dans, A Rostom, CP Cannon, D Henry, David Henry, E Masso Gonzalez, EL Fosbol, Fiona Mary Turnbull, JJ Deeks, JM Scheiman, L Garcia Rodriguez, P Kearney, P McGettigan, P McGettigan, Patricia McGettigan, S Hernandez-Dıaz, S Singh, S Trelle, SL Collins, T Grosser, V Strand   +20 more
core   +3 more sources

Self‐supportive Three‐Way Photoelectrochemical System Achieving Uranium Recycling, Organic Oxidation, and Electricity Generation in Complex Waters

Advanced Functional Materials, EarlyView.
A self‐sustaining solar photoelectrochemical cell (SS‐PEC) is developed to recover uranium from aqueous UO22+ with concurrent organic oxidation and electricity production. The monolithical photoanode directly captures electrons from organic compounds, leading to the oxidation of organic compounds and the decomposition of uranium‐organic complexes ...
Yumei Wang, Qingming Zeng, Haodong Ji, Rongzhong Wang, Jiachen Wang, Yanjun Wen, Wonyong Choi, Qingyi Zeng   +7 more
wiley   +1 more source

Ibuprofen: Synthesis, production and properties [PDF]

Hemijska Industrija, 2003
Since its introduction in 1969, ibuprofen has become one of the most common painkillers in the world. Ibuprofen in an NSAID (non-steroidal anti-inflammatory drug) and like other drugs of its class it possesses analgetic, antipyretic and anti-inflammatory
Mijin Dušan Ž., Stanković Milena, Petrović Slobodan D.   +2 more
doaj   +1 more source

Stereotypical escape behavior in Caenorhabditis elegans allows quantification of nociceptive stimuli levels

, 2016
Experiments of pain with human subjects are difficult, subjective, and ethically constrained. Since the molecular mechanisms of pain transduction are reasonably conserved among different species, these problems are partially solved by the use of animal ...
Leung, Kawai, Mohammadi, Aylia, Nemenman, Ilya, Ryu, William S.   +3 more
core   +2 more sources

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Ibuprofen as an Emerging Contaminant of Concern: Occurrence in Southeast Asia Water Environment [PDF]

E3S Web of Conferences
Ibuprofen is the third most salable pharmaceutical worldwide even being sold in the absence of prescription. This drug is not thoroughly metabolized and excreted into wastewater as an unchanged molecule and its metabolites.
Trianda Yenni, Adityosulindro Sandyanto, Moersidik Setyo Sarwanto   +2 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source