Results 231 to 240 of about 159,080 (332)

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

VCL/ICAM-1 pathway is associated with lung inflammatory damage in SARS-CoV-2 Omicron infection. [PDF]

open access: yesNat Commun
Xue M   +27 more
europepmc   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk   +3 more
wiley   +1 more source

Effect of fibrin on the expression of adhesion molecules (ICAM-1, ITGAV, and ITGB3) in unrestricted somatic stem cells. [PDF]

open access: yesHematol Transfus Cell Ther
Khaseb S   +7 more
europepmc   +1 more source

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra   +9 more
wiley   +1 more source

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

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