Results 51 to 60 of about 21,323,950 (308)

Reduction of Endothelial Nitric Oxide Increases the Adhesiveness of Constitutive Endothelial Membrane ICAM-1 through Src-Mediated Phosphorylation

Frontiers in Physiology, 2018
Nitric oxide (NO) is a known anti-adhesive molecule that prevents platelet aggregation and leukocyte adhesion to endothelial cells (ECs). The mechanism has been attributed to its role in the regulation of adhesion molecules on leukocytes and the adhesive
Feng Gao, Brandon P. Lucke-Wold, Brandon P. Lucke-Wold, Xiang Li, Aric F. Logsdon, Aric F. Logsdon, Li-Chong Xu, Sulei Xu, Kyle B. LaPenna, Huaqi Wang, Huaqi Wang, M. A. Hassan Talukder, Christopher A. Siedlecki, Jason D. Huber, Charles L. Rosen, Pingnian He   +15 more
doaj   +1 more source

Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development. [PDF]

PLoS ONE, 2013
BACKGROUND: In Taiwan, oral cancer has causally been associated with environmental carcinogens. Intercellular adhesion molecule (ICAM)-1, a cell adhesion molecule with a key role in inflammation and immunosurveillance, was implicated in carcinogenesis by
Chiao-Wen Lin, Chun-Yi Chuang, Chih-Hsin Tang, Junn-Liang Chang, Liang-Ming Lee, Wei-Jiunn Lee, Jyh-Ming Chow, Shun-Fa Yang, Ming-Hsien Chien   +8 more
doaj   +1 more source

ADAM10-Mediated Cleavage of ICAM-1 Is Involved in Neutrophil Transendothelial Migration

Cells, 2021
To efficiently cross the endothelial barrier during inflammation, neutrophils first firmly adhere to the endothelial surface using the endothelial adhesion molecule ICAM-1. Upon actual transmigration, the release from ICAM-1 is required.
Sofia K. H. Morsing, Timo Rademakers, Sanne L. N. Brouns, Anne-Marieke D. van Stalborch, Marjo M. P. C. Donners, Jaap D. van Buul   +5 more
doaj   +1 more source

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

Advanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan, David Bürger, Gunther Eggeler, Oleg Shchyglo, Ingo Steinbach, Muhammad Adil Ali   +5 more
wiley   +1 more source

Combined measurement of soluble and cellular ICAM-1 among children with Plasmodium falciparum malaria in Uganda

Malaria Journal, 2010
Background Intercellular adhesion molecule-1 (ICAM-1) is a cytoadhesion molecule implicated in the pathogenesis of Plasmodium falciparum malaria. Elevated levels of soluble ICAM-1 (sICAM-1) have previously been reported with increased malaria disease ...
Cserti-Gazdewich Christine M, Dzik Walter H, Erdman Laura, Ssewanyana Isaac, Dhabangi Aggrey, Musoke Charles, Kain Kevin C   +6 more
doaj   +1 more source

Multimodal Data‐Driven Microstructure Characterization

Advanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang, Santiago Benito, Özge Özgün, Sebastian Weber, Markus Stricker   +4 more
wiley   +1 more source

An analysis of the binding characteristics of a panel of recently selected ICAM-1 binding Plasmodium falciparum patient isolates.

PLoS ONE, 2014
The basis of severe malaria pathogenesis in part includes sequestration of Plasmodium falciparum-infected erythrocytes (IE) from the peripheral circulation.
Aymen M Madkhali, Mohammed O Alkurbi, Tadge Szestak, Anja Bengtsson, Pradeep R Patil, Yang Wu, Saeed A Al-Harthi, Anja T R Jensen, Richard Pleass, Alister G Craig   +9 more
doaj   +1 more source

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

Frontiers in Immunology, 2017
The interaction between intercellular adhesion molecules (ICAM) and the integrin leukocyte function-associated antigen-1 (LFA-1) is crucial for the regulation of several physiological and pathophysiological processes like cell-mediated elimination of ...
David Núñez, David Núñez, David Núñez, Laura Comas, Laura Comas, Laura Comas, Pilar M. Lanuza, Pilar M. Lanuza, Diego Sánchez-Martinez, Diego Sánchez-Martinez, Marta Pérez-Hernández, Marta Pérez-Hernández, Elena Catalán, María Pilar Domingo, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Julián Pardo, Julián Pardo, Julián Pardo, Julián Pardo, Eva M. Gálvez, Eva M. Gálvez   +22 more
doaj   +1 more source

ICAMs are dispensable for influenza clearance and anti-viral humoral and cellular immunity

Frontiers in Immunology, 2023
αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell communications is still debated.
Stav Kozlovski, Ofer Regev, Anita Sapoznikov, Marina Kizner, Hagit Achdout, Ekaterina Petrovich-Kopitman, Jacob Elkahal, Yoseph Addadi, Fernanda Vargas E. Silva Castanheira, Sara W. Feigelson, Paul Kubes, Noam Erez, Natalio Garbi, Ronen Alon   +13 more
doaj   +1 more source

ICAM-1 receptors and cold viruses

Pharmaceutica Acta Helvetiae, 2000
Human rhinoviruses (HRVs), the single most important etiologic agent of common colds, are small viruses composed of an icosahedral protein shell that encapsidates a single, positive RNA strand. Multiplication of HRVs occurs in the cytoplasm of the host cell.
Bella, Jordi, Rossmann, Michael G.
openaire   +2 more sources