Frontiers in Immunology, 2022 The nasal cavity is an important site of allergen entry. Hence, it represents an organ where trans-epithelial allergen penetration and subsequent IgE-mediated allergic inflammation can potentially be inhibited.
Ines Zettl +14 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
eLifeEpithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical membrane domain into bile canaliculi and ducts, which are not ...
Cristina Cacho-Navas +20 more
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Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1 [PDF]
Infection and Immunity, 1997 The adhesion of Plasmodium falciparum-infected erythrocytes is thought to play a central role in the pathogenesis of severe malaria. ICAM-1 has been identified as one of the host receptors for parasitized erythrocytes and has been implicated as being involved in progression to cerebral malaria.
Craig, A +6 more
openaire +3 more sources
Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions. [PDF]
, 2017 Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The
Bardel, Bernadette +11 more
core +2 more sources
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
Advanced Science, EarlyView.This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma +11 more
wiley +1 more source
Annals of Agricultural and Environmental Medicine, 2016 Introduction The term ‘subarachnoid haemorrhage’ (SAH) stands for bleeding into the subarachnoid space, regardless of its source. It may be of primary character when the source of bleeding is situated within the subarachnoid space.
Abu-Sitta Al-Drawi +8 more
doaj +1 more source
Comparison of Serum Levels of Cell Adhesion Molecules (E-selectin, P-selectin, Icam-1, Vcam-1, Lrg-1) in Placental Invasion and Adhesion Anomalies With Patients With Vaginal Delivery and Former Cesarerean [PDF]
, 2022 Rutkay Ersuz +2 more
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ICAM-1–Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma [PDF]
Clinical Cancer Research, 2016 Abstract Purpose: Portal vein tumor thrombus (PVTT) is a major complication of hepatocellular carcinoma (HCC) and is associated with poor survival. Long noncoding RNAs (lncRNA) contribute to HCC metastasis, but whether and how lncRNAs affect PVTT development remains unclear.
Weixing, Guo +10 more
openaire +2 more sources
A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]
, 2003 The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes +51 more
core +1 more source