Results 71 to 80 of about 27,302,336 (342)

Increased ICAM-1 expression in aortic disease [PDF]

Journal of Vascular Surgery, 1993
In this investigation we evaluated the expression of vascular adhesion molecules: intercellular adhesion molecule-1 (ICAM-1), E-selectin, and vascular cell adhesion molecule-1 (VCAM-1) in normal and diseased aorta.Aortic tissue was obtained during operations for abdominal aortic aneurysms (AAA) (inflammatory, n = 3, noninflammatory, n = 6), aortic ...
C A, Davis, W H, Pearce, G K, Haines, M, Shah, A E, Koch   +4 more
openaire   +2 more sources

Rafting of Ni‐Based Superalloys Under Multiaxial Load as Understood by Phase‐Field Simulations and Critical Experiments

Advanced Engineering Materials, EarlyView.
Phase‐field simulations coupled with dislocation‐density‐based crystal plasticity modeling reproduce γ′ rafting behavior in single‐crystal Ni‐based superalloys under varied loading conditions. The model captures both macroscopic creep and microscopic morphology evolution, with results matching high‐temperature creep experiments.
Micheal Younan, David Bürger, Gunther Eggeler, Oleg Shchyglo, Ingo Steinbach, Muhammad Adil Ali   +5 more
wiley   +1 more source

ICAM-1 Antisense Oligodeoxynucleotide Improves Islet Allograft Survival and Function

Cell Transplantation, 2000
Expression of intercellular adhesion molecule-1 (ICAM-1) and its ligand, leukocyte function antigen-1 (LFA-1), after pancreatic islet transplantation may affect both nonspecific and alloantigen-specific phases of graft destruction.
Stephen M. Katz M.D., Frank Bennett, Kim Stecker, James H. Clark, Tommy Phan, Mou-Er Wang, Barry D. Kahan, Stanislaw M. Stepkowski   +7 more
doaj   +1 more source

ICAMs are dispensable for influenza clearance and anti-viral humoral and cellular immunity

Frontiers in Immunology, 2023
αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell communications is still debated.
Stav Kozlovski, Ofer Regev, Anita Sapoznikov, Marina Kizner, Hagit Achdout, Ekaterina Petrovich-Kopitman, Jacob Elkahal, Yoseph Addadi, Fernanda Vargas E. Silva Castanheira, Sara W. Feigelson, Paul Kubes, Noam Erez, Natalio Garbi, Ronen Alon   +13 more
doaj   +1 more source

Autophagy facilitates cytokine-induced ICAM-1 expression [PDF]

Innate Immunity, 2013
ICAM-1 can be induced by inflammatory cytokines such as IFN-γ and TNF-α. This study investigated whether autophagy regulates ICAM-1 given that autophagy facilitates signaling of these two cytokines. Exogenous IFN-γ induced ICAM-1 in human lung epithelial A549 cells carrying wild type p53, a transcription factor reported for ICAM-1, but not in PC14PE6 ...
Chi-Yun, Wang, Tzu-Hui, Chiang, Chia-Ling, Chen, Po-Chun, Tseng, Shun-Yi, Chien, Yi-Jui, Chuang, Tsan-Tzu, Yang, Chia-Yuan, Hsieh, Pui-Ching, Choi, Chiou-Feng, Lin   +9 more
openaire   +2 more sources

ICAM-1 controls development and function of ILC2

Journal of Experimental Medicine, 2018
Group 2 innate lymphoid cells (ILC2s) are emerging as key players in the pathogenesis of allergic airway inflammation. The mechanisms regulating ILC2, however, are not fully understood.
Aihua Lei, Q. Xiao, Gaoyu Liu, Kun Shi, Qiong Yang, Xing Li, Yu-feng Liu, Haikun Wang, W. Cai, Yu-juan Guan, D. Gabrilovich, Jie Zhou   +11 more
semanticscholar   +1 more source

Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation [PDF]

, 2003
Introduction and methods: The reaction of superoxide anions and NO not only results in a decreased availability of NO, but also leads to the formation of peroxynitrite, the role of which in the cardiovascular system is still discussed controversially. In
Gloe, Torsten, Keller, Matthias, Klauss, Volker, Krötz, Florian, Pohl, Ulrich, Schiele, Thomas M., Sohn, Hae-Young, Theisen, Karl, Zahler, Stefan   +8 more
core   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Combined effects of icam-1 single-nucleotide polymorphisms and environmental carcinogens on oral cancer susceptibility and clinicopathologic development. [PDF]

PLoS ONE, 2013
BACKGROUND: In Taiwan, oral cancer has causally been associated with environmental carcinogens. Intercellular adhesion molecule (ICAM)-1, a cell adhesion molecule with a key role in inflammation and immunosurveillance, was implicated in carcinogenesis by
Chiao-Wen Lin, Chun-Yi Chuang, Chih-Hsin Tang, Junn-Liang Chang, Liang-Ming Lee, Wei-Jiunn Lee, Jyh-Ming Chow, Shun-Fa Yang, Ming-Hsien Chien   +8 more
doaj   +1 more source

ICAM-1 regulates macrophage polarization by suppressing MCP-1 expression via miR-124 upregulation

OncoTarget, 2017
Intercellular adhesion molecule-1 is the adhesion molecule mediating leukocyte firm adhesion to endothelial cells, plays a critical role in subsequent leukocyte transmigration.
W. Gu, L. Yao, Lexing Li, Jianping Zhang, Aaron T. Place, R. Minshall, Guoquan Liu   +6 more
semanticscholar   +1 more source