Results 101 to 110 of about 7,242 (224)

Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]

, 2019
Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary, Chesney, Margaret, Conley, Yvette P, Kober, Kord M, Levine, Jon D, Melisko, Michelle, Miaskowski, Christine, Paul, Steven M, Schumacher, Mark, Topp, Kimberly   +9 more
core  

The omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) reverses corticosterone-induced changes in cortical neurons [PDF]

, 2017
Background: Chronic exposure to the glucocorticoid hormone corticosterone exerts cellular stress-induced toxic effects that have been associated with neurodegenerative and psychiatric disorders.
Cryan, John F., Dinan, Timothy G., Green, Holly F., Kelly, Philip M., Nolan, Yvonne M., Pusceddu, Matteo M., Robertson, Ruairi C., Stanton, Catherine   +7 more
core   +1 more source

Division of Natural Products Chemistry [PDF]

, 2008
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
Awale Suresh, 手塚 康弘, 門田 重利   +2 more
core   +1 more source

Resveratrol Demonstrates Antimicrobial Effects Against Propionibacterium acnes In Vitro [PDF]

, 2014
IntroductionResveratrol (3,5,4'-trihydroxystilbene) is an antioxidant that has multiple biologic effects including antimicrobial properties. Acne vulgaris is a disease of the pilosebaceous unit, characterized by an inflammatory host immune response to ...
Emma J. M. Taylor, Jackson Champer, Jenny Kim, Yang Yu   +3 more
core   +2 more sources

Letter to the Editor in response to the article “Dysregulation of miR‐21‐5p in diabetic nephropathy and its role in inflammatory response”

Journal of Diabetes Investigation, Volume 17, Issue 4, Page 705-706, April 2026.
Ciyu Zhao
wiley   +1 more source

Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects

Stem Cells International, 2016
Bone tissue engineering technique is a promising strategy to repair large-volume bone defects. In this study, we developed a 3-dimensional construct by combining icariin (a small-molecule Chinese medicine), allogeneic bone marrow-derived mesenchymal stem
Tianlin Liu, Xin Zhang, Yuan Luo, Yuanliang Huang, Gang Wu   +4 more
doaj   +1 more source

Icariin as a Treatment Proposal in Mammalian Reproduction

Pharmaceuticals
Icariin (ICA), one of the main active components of Herba Epimedii, is a natural prenylated flavonol glycoside that possesses a wide range of pharmacological effects, including antioxidant, antiosteoporotic, anti-aging, neuroprotective, immunomodulatory, antitumor, and aphrodisiac effects, and prevents numerous health disorders, such as cardiovascular ...
Manuel Sánchez-Gutiérrez, Aleli Julieta Izquierdo-Vega, Eduardo Osiris Madrigal-Santillán, Claudia Velázquez-González, Jeannett Alejandra Izquierdo-Vega   +4 more
openaire   +3 more sources

Synergistic effect of pulsed electromagnetic fields and saffron extract on osteogenic differentiation of bone marrow mesenchymal stem cells [PDF]

, 2017
Introduction: Pulsed electromagnetic fields (PEMFs) are usually used to treat non-union fractures. Saffron is a medicinal plant with various pharmacologic effects.
Asadi-Samani, Majid., Baharara, Javad., Mousavi, Marzieh., Ramezani, Tayebeh.   +3 more
core   +1 more source

Flavones induce neutrophil apoptosis by down-regulation of Mcl-1 via a proteasomal-dependent pathway [PDF]

, 2013
Neutrophil apoptosis and subsequent nonphlogistic clearance by surrounding phagocytes are key to the successful resolution of neutrophilic inflammation, with dysregulated apoptosis reported in multiple human inflammatory diseases.
Adriano G. Rossi, Carl S. Tucker, Christopher D. Lucas, Christopher Haslett, David A. Dorward, Haslett C., Hideshima T., John A. Marwick, Keith C. Allen, Laura J. Hoodless, Lauren A. Melrose, Leitch A. E., McGrath E. E., Meagher L. C., O'Flaherty J. T., Rithidech K. N., Rodger Duffin, Watson R. W., Westerfield M.   +18 more
core   +1 more source

Icariin, a flavonoid with anti-cancer effects, alleviated paclitaxel-induced neuropathic pain in a SIRT1-dependent manner

Molecular Pain, 2018
Background One of the most common side effects of paclitaxel was dosage-dependently painful neuropathy. Various reports indicated that spinal neuroinflammation was involved in paclitaxel-induced neuropathic pain.
Yulong Gui, Jie Zhang, Liang Chen, Shunyuan Duan, Jing Tang, Wei Xu, Aiyuan Li   +6 more
doaj   +1 more source