Results 61 to 70 of about 7,149 (225)

Icariin Prevents Diabetes-Induced Bone Loss in Rats by Reducing Blood Glucose and Suppressing Bone Turnover

Molecules, 2019
Diabetic Osteoporosis (DOP) is a common metabolic bone disease, characterized by decreased bone mineral density (BMD) and destruction of bone microstructure.
Shanshan Qi, Jia He, Hongxing Zheng, Chen Chen, Shiqiang Lan   +4 more
doaj   +1 more source

Enhancement of Icariin Aphrodisiac Effect by Solid-SNEDDS Method Using Shark Liver Oil Phase [PDF]

, 2023
The Epimedium brevicornu Maxim plant contains icariin, a flavonoid compound known for its aphrodisiac effects. However, icariin has low solubility and bioavailability. This study aims to find the best formula for S-SNEDDS icariin, its physical properties,
Indratmoko, Septiana, Nurani, Laela H., Wahyuningsih, Iis   +2 more
core   +2 more sources

Enhancement of Epimedium Fried with Suet Oil Based on in Vivo Formation of Self-Assembled Flavonoid Compound Nanomicelles

Molecules, 2012
The purpose of this work was to research the enhancement of Epimedium fried with suet oil based on the in vivo formation self-assembled flavonoid nanomicelles.
Xiao-Bin Jia, Xin Jin, Ying-Jie Wei, Xiao-Bin Tan, Zhen-Hai Zhang, Li Cui, E Sun   +6 more
doaj   +1 more source

HIF-1 signalling pathway was identified as a potential new pathway for Icariin’s treatment against Alzheimer’s disease based on preclinical evidence and bioinformatics

Frontiers in Pharmacology, 2022
Aim: Alzheimer’s disease (AD) is a neurodegenerative condition that is characterized by the gradual loss of memory and cognitive function. Icariin, which is a natural chemical isolated from Epimedii herba, has been shown to protect against AD.
Mingyao You, Ping Yuan, Liangqian Li, Hongbei Xu   +3 more
doaj   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, Volume 13, Issue 5, 4 March 2026.
ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation rates ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Comprehensive study for investigating the mechanisms by which dietary icariin prevents ferroptosis in aged-related osteoporosis

Food Science and Human Wellness
Icariin is a natural product that possesses numerous pharmaceutical properties. Thus, this study aimed to investigate the molecular mechanism by which icariin prevents ferroptosis in aged-related osteoporosis.
Maopeng Wang, Yuanlin Wang, Yong Zeng, Zhipeng Tian, Liuhai Xu, Xinzhi Li, Lei Wang, Bing Li, You Zhou, Jun Liu   +9 more
doaj   +1 more source

Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

Scientific Reports, 2017
Typically, bone regenerative medicine is applied to repair bone defects in patients with osteoporosis. Meanwhile, there is an urgent need to develop safe and cheap drugs that induce bone formation.
Yuqiong Wu, LingYan Cao, Lunguo Xia, Qianju Wu, Jie Wang, Xiao Wang, Lianyi Xu, Yuning Zhou, Yuanjin Xu, Xinquan Jiang   +9 more
doaj   +1 more source

Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma [PDF]

, 2015
BACKGROUND: Extranodal NK/T-cell lymphoma (ENKL) is an aggressive hematological malignancy associated with Epstein–Barr virus (EBV) infection. It is often resistant to conventional chemotherapy and has a poor prognosis.
Bobin Chen, Jinfeng Wu, Norio Shimizu, Songmei Wang, Ting Wu, Xianxian Sui, Xiaoping Xu, Xuanyi Wang, Zhiguang Lin   +8 more
core   +1 more source

Anti-inflammatory and immunoregulatory effects of icariin and icaritin

Biomedicine & Pharmacotherapy, 2022
Inflammation and immunity dysregulation have received widespread attention in recent years due to their occurrence in the pathophysiology of many conditions. In this regard, several pharmacological studies have been conducted aiming to evaluate the potential anti-inflammatory and immunomodulatory effects of phytochemicals.
Zhangyang, Bi, Wei, Zhang, Xiaoyan, Yan
openaire   +2 more sources

Icariin as a potential anticancer agent: a review of its biological effects on various cancers

Frontiers in Pharmacology, 2023
Numerous chemical compounds used in cancer treatment have been isolated from natural herbs to address the ever-increasing cancer incidence worldwide. Therein is icariin, which has been extensively studied for its therapeutic potential due to its anti ...
Fang-Yuan Liu, Dan-Ni Ding, Yun-Rui Wang, Shao-Xuan Liu, Cheng Peng, Fang Shen, Xiao-Ya Zhu, Chan Li, Li-Ping Tang, Feng-Juan Han   +9 more
doaj   +1 more source