Results 111 to 120 of about 3,621,494 (339)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The Effect of Sugar Addition and Time of Storage on Physical Quality of Fermented Milk

open access: yesJurnal Ilmu dan Teknologi Hasil Ternak, 2012
Fermented milk  is one of processing milk used one or more microorganism. The objectives of the research were to find out the effect of sugar addition and time of storage on physical quality of fermented milk. This research was using factorial Randomized
Ice Gianti, Herly Evanuarini
doaj  

Simulation and investigation of tire tread blocks interaction with ice / Padangos protektoriaus elementų sąveikos su ledu modeliavimas ir tyrimas

open access: yesMokslas: Lietuvos Ateitis, 2017
The car tire is an essential subject analysing its interaction with the road. From tire’s tread condition, geometry and rubber compound depends grip and vehicle stability.
Andrius Ružinskas
doaj   +1 more source

Spitzer Observations of CO2 Ice Towards Field Stars in the Taurus Molecular Cloud

open access: yes, 2005
We present the first Spitzer Infrared Spectrograph observations of the 15.2 micron bending mode of CO2 ice towards field stars behind a quiescent dark cloud.
Caux E.   +12 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Geomorphological Evidence of Ice Activity on Mars Surface at Mid-Latitudes

open access: yesRemote Sensing
Extensive radar investigations, observed spectral signatures, geomorphological, and paleoclimate modeling support the presence of mid- to low-latitude ground ice on Mars. The presence of near-surface ice and glacial features has been proposed in Ismenius
Marco Moro   +9 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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