Results 71 to 80 of about 1,713,620 (300)
Reconstructing ice dynamics in the central sector of the last British-Irish Ice Sheet [PDF]
, 2010 The central sector (NW England and Scottish borders) of the last British-Irish Ice Sheet exhibits a palimpsest glacial geological and geomorphological signature characteristic of multi-phase ice flow and ice-marginal fluctuations. Despite its influential
LIVINGSTONE, STEPHEN,JOHN +1 more
core
New modeling of the Vostok ice flow line and implication for the glaciological chronology of the Vostok ice core [PDF]
, 2004 We have used new spaceborne (elevation) and airborne (ice thickness) data to constrain a 2D1/2 model of snow accumulation and ice flow along the Ridge B-Vostok station ice flow line (East Antarctica).
Ritz, C. +6 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
IEEE AccessThe development of nanofunctionalized transformer oils has sparked growing interest in understanding their electrical discharge behavior. This review presents a comprehensive analysis of diagnostic methods used to investigate partial discharges and ...
Kristian Glajc +2 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
A New Guitar Teaching Philosophy A New Guitar Teaching Philosophy
Acta Universitaria, 2012 In this present work it is given an opinion for a new approach to guitar teaching philosophy in a sufficiently sophisticated way, which surpasses up to now all known looks. With a goal to shed light on this important topic, this work will introduce a new
Ice B. Risteski
doaj
Object-Background Blending Augmentation Method for Object Detection Systems
IEEE AccessReliable object detection in aerial imagery is critical for applications such as drone surveillance, disaster monitoring, and infrastructure protection.
Ladislav Hric +2 more
doaj +1 more source
ICE VII, THE DENSEST FORM OF ICE
Proceedings of the National Academy of Sciences, 1964 In the pressure range 0-25 kilobars there occur 7 different crystalline modifications of ice,(1) whereas from 25 kbar up to the highest pressure so far tried, 200 kbar, only a single form occurs:(2) ice VII, of density about 1.7 gm cm^-3. Ice VII thus seems in some sense to be an "ultimate" crystalline form of ice, and its structure is therefore of ...
B, Kamb, B L, Davis
openaire +3 more sources