Results 61 to 70 of about 1,713,620 (300)
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
MASSIVE: A scalable framework for agent-based scheduling of micro-grids using market mechanisms
Energy InformaticsWith the increasing share of distributed renewable energy sources the need arises to store excess energy and/or to shift demands to match the given supply. To coordinate multiple suppliers and demands in a local energy-system different control approaches
Jakob M. Fritz +3 more
doaj +1 more source
Signal Prediction Using U-Net CNN: Beyond Traditional RNN Approaches
IEEE AccessThis paper studies signal prediction in settings where the target signal is not a continuation of an observed history but must be inferred from other simultaneously measured signals.
Marek Ruzicka +3 more
doaj +1 more source
Dissociation Behavior of Dislocations in Ice
Crystals, 2019 Dislocations in ice behave very differently from those in other materials due to the very low energies of stacking faults in the ice basal plane. As a result, the dislocations dissociate on the basal plane, from a perfect dislocation into two partial ...
Takeo Hondoh
doaj +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Stellar encounters in the solar neighbourhood and the special case of GJ 710
Astronomy & AstrophysicsAims. We present a comprehensive characterisation of close stellar encounters in the solar vicinity, with a particular focus on placing the predicted fly-by of GJ 710 in context.
Fernandez-Puig Eloi +4 more
doaj +1 more source
MedEdPORTAL, 2011 Abstract This is a high-fidelity human patient simulation involving a severely hypothermic patient requiring invasive measures to rewarm the patient's core temperature. Altered physiology, along with medical and traumatic scenarios that put the patient at risk for severe hypothermia, is also addressed.
Michael Smith, Thomas Noeller
openaire +2 more sources
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source