Results 51 to 60 of about 45,044 (305)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diffuse scattering in ice Ih

, 2014
Single crystals of ice Ih, extracted from the subglacial Lake Vostok accretion ice layer (3621 m depth) were investigated by means of diffuse x-ray scattering and inelastic x-ray scattering.
Bosak, Alexeï, Bulat, Sergey, Chernyshov, Dmitry, Ezhov, Victor, Krisch, Michael, Wehinger, Björn   +5 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Ice Accretion Forecast for Power Grids Based on Pangu Model and Machine Learning Correction: A Case Study on Late December 2021 in Xinjiang, China

Atmosphere
During late December 2021, an ice accretion disaster occurred in North Xinjiang, especially in the western part. It is found that the meteorological conditions suitable for the occurrence of ice accretion disasters are when the temperature is between −14
Yujie Li, Yang Yang, Meng Li, Mingguan Zhao, Xiaojing Yang   +4 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Research on Ice Accretion Prediction Model for Wind Turbine Blades Based on Multi-Layer Perceptron Neural Network

发电技术
ObjectivesIn cold regions, the icing problem on wind turbine blades significantly reduces power generation efficiency and increases safety risks, making accurate icing prediction technology crucial. To improve the accuracy of ice accretion prediction for
HAN Bin, ZENG Zhixiang, KONG Fanxin, XIE Nan, LIU Zhiqiang   +4 more
doaj   +1 more source

Metatranscriptomic and Metagenomic Analysis of Biological Diversity in Subglacial Lake Vostok (Antarctica)

Biology, 2020
A combined metatranscriptomic and metagenomic study of Vostok (Antarctica) ice core sections from glacial, basal, and lake water accretion ice yielded sequences that indicated a wide variety of species and possible conditions at the base of the glacier ...
Colby Gura, Scott O. Rogers
doaj   +1 more source

Ice Lines, Planetesimal Composition and Solid Surface Density in the Solar Nebula

, 2008
To date, there is no core accretion simulation that can successfully account for the formation of Uranus or Neptune within the observed 2-3 Myr lifetimes of protoplanetary disks.
A'Hearn, Abe, Aikawa, Aikawa, Alexander, Alibert, Allen, Anders, Baines, Balbus, Barucci, Barzel, Bell, Boss, Caselli, Cazaux, Charles A. Beichman, Charnley, Chiang, Chiang, Ciesla, Ciesla, Collings, D'Alessio, Dodson-Robinson, Dullemond, Ferguson, Flasar, Fraser, Gail, Garrod, Grundy, Haisch, Hallenbeck, Hasegawa, Hasegawa, Hawley, Hawley, Hayashi, Helling, Herbst, Hersant, Hersant, Hersant, Hornekaer, Hubbard, Hubickyj, Hussmann, Ilgner, Jessberger, Karen Willacy, Katz, Keller, Kippenhahn, Kretke, Lodders, Lodders, Lodders, Lopes, Lynden-Bell, Lyra, Mihalas, Millar, Milsom, Neal J. Turner, Owen, Owen, Owen, Peter Bodenheimer, Pollack, Press, Pringle, Reyes-Ruiz, Rivkin, Ruden, Ruden, Ruffle, Sandford, Sarah E. Dodson-Robinson, Semenov, Shakura, Spohn, Stepinski, Tielens, Tielens, Tsiganis, Turner, Umebayashi, Umebayashi, van Boekel, Weidenschilling, Willacy, Willacy, Womack, Woods, Öberg   +95 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling of Ice Accretion over Aircraft Wings Using a Compressible OpenFOAM Solver

International Journal of Aerospace Engineering, 2019
A method to simulate ice accretion on an aircraft wing using a three-dimensional compressible Navier-Stokes solver, a Eulerian droplet flow field model, a mesh morphing model, and a thermodynamic model, is presented in this paper.
Sibo Li, Roberto Paoli
doaj   +1 more source