Results 91 to 100 of about 737,718 (307)
Annotated bibliography of the Russian literature on glaciology for 2014
Лëд и снег, 2016 The proposed annual bibliography continues annotated lists of the Russian-language literature on glaciology that were regularly published in the past. It includes 271 references grouped into the following ten sections: 1) general issues of glaciology; 2)
V. M. Kotlyakov, L. P. Chernova
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Rapid increase in atmospheric iodine levels in the North Atlantic since the mid-20th century
Nature Communications, 2018 Despite its chemical importance, the evolution of atmospheric iodine concentrations over time is unknown. Here, the authors show that North Atlantic atmospheric iodine levels have tripled since 1950, and propose ozone pollution and enhanced biological ...
Carlos A. Cuevas +14 more
doaj +1 more source
Sulfur mass loading of the atmosphere from volcanic eruptions: Calibration of the ice core record on basis of sulfate aerosol deposition in polar regions from the 1982 El Chichon eruption [PDF]
Major volcanic eruptions disperse large quantities of sulfur compound throughout the Earth's atmosphere. The sulfuric acid aerosols resulting from such eruptions are scavenged by snow within the polar regions and appear in polar ice cores as elevated ...
Laj, Paolo, Sigurdsson, Haraldur
core +1 more source
, 2016 WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Elementa: Science of the Anthropocene, 2019 The cryosphere, which comprises a large portion of Earth’s surface, is rapidly changing as a consequence of global climate change. Ice, snow, and frozen ground in the polar and alpine regions of the planet are known to directly impact atmospheric ...
Jennie L. Thomas +34 more
doaj +1 more source
6.0.C.1 Hands-on Phase Properties of Gases [PDF]
, 2016 WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source