Results 61 to 70 of about 737,718 (307)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Photodesorption of water ice: a molecular dynamics study

, 2008
Absorption of ultraviolet radiation by water ice coating interstellar grains can lead to dissociation and desorption of the ice molecules. These processes are thought to be important in the gas-grain chemistry in molecular clouds and protoplanetary disks,
Aikawa, Al-Halabi, Al-Halabi, Andersson, Andersson, Berendsen, Bergeld, Bergin, Bergin, Boonman, Caselli, Ceccarelli, Cuppen, d'Hendecourt, d'Hendecourt, Dalgarno, Dobbyn, Dominik, E. F. van Dishoeck, Ehrenfreund, Elles, Fraser, Garrod, Gerakines, Ghormley, Gibb, Hagen, Hartquist, Holtom, Jewitt, Jorgensen, Kimmel, Kimmel, Kobayashi, Léger, Mayer, Murakawa, Nishi, O'Neill, Palumbo, Pontoppidan, Pontoppidan, Pontoppidan, Prasad, S. Andersson, Shen, Smith, Snell, Snell, Spaans, Stäuber, Stäuber, van Dishoeck, van Harrevelt, van Harrevelt, Watanabe, Watanabe, Watanabe, Westley, Westley, Whittet, Willacy, Willner, Yabushita   +63 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Arena ice quality and perspectives on optimizing performance and addressing emerging challenges

Scientific Reports
Maintaining optimal ice surfaces in arenas is essential for ensuring athlete performance and safety in sports such as hockey, figure skating, and curling. This study combines expert survey responses from 55 North American ice arena managers with existing
Ryan H. S. Hutchins, Yanan Li, Greg Taylor, Dave Loverock, Stefania Impellizzeri   +4 more
doaj   +1 more source

Saltwater icephobicity: Influence of surface chemistry on saltwater icing [PDF]

Scientific Reports, 2015
AbstractMost studies on icephobicity focus on ice formation with pure water. This manuscript presents studies to understand the influence of surfaces on saltwater ice nucleation and propagation. Experiments are conducted to quantify the influence of surface chemistry on saltwater ice nucleation and to understand the utility of superhydrophobic surfaces
Katherine Carpenter, Vaibhav Bahadur
openaire   +2 more sources

Anthropogenic signals recorded in an ice core from Eclipse Icefield, Yukon Territory, Canada [PDF]

, 2001
Trends in the annual flux of sulfate and nitrate in a new ice core collected at an elevation of 3017 m on Eclipse Icefield, 45 km northeast of Mt. Logan were examined to determine the effect of anthropogenic activity on precipitation chemistry in the ...
Wake, Cameron P, Yalcin, Kaplan
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Chlorine peroxide reaction explains observed wintertime hydrogen chloride in the Antarctic vortex

Communications Earth & Environment
It is well established that the drastic ozone loss in the Antarctic stratosphere, commonly known as the ozone hole, is primarily driven by gas-phase and heterogeneous chemical processes. While chemistry transport models generally reproduce observed ozone
Jens-Uwe Grooß, Rolf Müller, John N. Crowley, Michaela I. Hegglin   +3 more
doaj   +1 more source

The effects of methanol on the trapping of volatile ice components [PDF]

, 2015
The evaporation of icy mantles, which have been formed on the surface of dust grains, is acknowledged to give rise to the rich chemistry that has been observed in the vicinity of hot cores and corinos.
Adriaens, Ayotte, Backus, Bar-Nun, Blake, Bockelee-Morvan, Bolina, Bolina, Boogert, Brown, Burke, Burke, Codella, Collings, Cruikshank, Daren J. Burke, Dartois, De Jong, DelloRusso, Edridge, Ehrenfreund, Ehrenfreund, Fraser, Garozzo, Gibb, Goumans, Grim, Hagen, Herbst, Ioppolo, Jewitt, Klinger, Lellouch, Martín-Doménech, Merlin, Merlin, Mills, Notesco, Palumbo, Palumbo, Pontoppidan, Smith, Smith, Souda, Souda, Souda, Viti, Wendy A. Brown, Whittet, Wolff, Yung   +50 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source