Results 101 to 110 of about 347,440 (309)
Variations in the conditions of sea ice in the northern part of Baffin Bay and North Open Water polynya influence human activity in northwestern Greenland through oceanic circulation and heat balance between air and sea.
Aoki, Teruo +19 more
core +1 more source
Ice core melt features in relation to Antarctic coastal climate [PDF]
Measurement of light intensity transmission was carried out on an ice core S100 from coastal Dronning Maud Land (DML). Ice lenses were observed in digital pictures of the core and recorded as peaks in the light transmittance record.
Roderik S.W. van de Wal +24 more
core +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Factors influencing the stable carbon isotopic composition of suspended and sinking organic matter in the coastal Antarctic sea ice environment [PDF]
A high resolution time-series analysis of stable carbon isotopic signatures in particulate organic carbon (δ13CPOC) and associated biogeochemical parameters in sea ice and surface waters provides an insight into the factors affecting δ13CPOC in the ...
Carson, D. S. +26 more
core +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Line-scan grey-scale intensity profile from the NGRIP2 ice core, Greenland
A continuous high-resolution record of digital images was obtained from the North Greenland Ice Core Project (NGRIP) ice core in the depth interval from 1330 m to the bedrock at 3085 m during the Greenland field seasons of 2000 and 2001.
Kipfstuhl, Sepp +2 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Decadal migration of Dome C inferred by global navigation satellite system measurements
Understanding the behaviour of domes under both contemporary and historical environmental conditions is essential to facilitate the study of dome-divide dynamics and the interpretation of ice core records.
Luca Vittuari +6 more
doaj +1 more source
A system for analysis of H2 and Ne in polar ice core samples [PDF]
This paper describes instrumentation and procedures developed to measure H2 and Ne in polar ice core samples. Gases are extracted from ice core samples by melting under vacuum.
E. S. Saltzman +4 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source

