Results 141 to 150 of about 312,748 (262)

An East Antarctic, sub-annual resolution water isotope record from the Mount Brown South Ice core. [PDF]

Sci Data
Gkinis V, Jackson S, Abram NJ, Plummer C, Blunier T, Harlan M, Kjær HA, Moy AD, Peensoo KM, Quistgaard T, Svensson A, Vance TR.   +11 more
europepmc   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Improved biomass burning emissions from 1750 to 2010 using ice core records and inverse modeling. [PDF]

Nat Commun
Zhang B, Chellman NJ, Kaplan JO, Mickley LJ, Ito T, Wang X, Wensman SM, McCrimmon D, Steffensen JP, McConnell JR, Liu P.   +10 more
europepmc   +1 more source

Organic Compounds in a Sub-Antarctic Ice Core: A Potential Suite of Sea Ice Markers. [PDF]

Geophys Res Lett, 2019
King ACF, Thomas ER, Pedro JB, Markle B, Potocki M, Jackson SL, Wolff E, Kalberer M.   +7 more
europepmc   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Reconciling ice core CO₂ and land-use change following New World-Old World contact. [PDF]

Nat Commun
King ACF, Bauska TK, Brook EJ, Kalk M, Nehrbass-Ahles C, Wolff EW, Strawson I, Rhodes RH, Osman MB.   +8 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Synchronizing volcanic, sedimentary, and ice core records of Earth's last magnetic polarity reversal. [PDF]

Sci Adv, 2019
Singer BS, Jicha BR, Mochizuki N, Coe RS.   +3 more
europepmc   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

East Greenland ice core dust record reveals timing of Greenland ice sheet advance and retreat. [PDF]

Nat Commun, 2019
Simonsen MF, Baccolo G, Blunier T, Borunda A, Delmonte B, Frei R, Goldstein S, Grinsted A, Kjær HA, Sowers T, Svensson A, Vinther B, Vladimirova D, Winckler G, Winstrup M, Vallelonga P.   +15 more
europepmc   +1 more source