Results 121 to 130 of about 208,369 (219)

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

Sea ice dynamics structure narwhal presence and seasonal movements in a Northwest Greenland fjord system. [PDF]

Sci Rep
Larsen JSK, Ladegaard M, Madsen PT, Olsen SM, Simon M.   +4 more
europepmc   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Reconstructing Great Lakes air temperature and ice dynamics data back to 1897. [PDF]

Sci Data
King K, Fujisaki-Manome A, Brant C, Cohn D, Peng I, Alofs K.   +5 more
europepmc   +1 more source

Directional Confinement Governed Ion Transport for Efficient Actuation

Advanced Materials, EarlyView.
Structural anisotropy provides an effective means to regulate ion transport in polymer electrolytes. Directionally aligned channels formed by freeze‐drying provide continuous pathways for ion migration, enhancing ion mobility and simultaneously improving the strain and blocking force of ionic actuators.
Yufei Zhang, Qiuchun Lu, Adit Gupta, Sen Wang, Xueyang Wang, Jian Yu, Xuanyi Hu, Daniel Mandler, Pooi See Lee   +8 more
wiley   +1 more source

Subglacial water flow and ice dynamics during glacial lake outburst floods observed from space. [PDF]

Nat Commun
Magnússon E, Drouin V, Pálsson F, Jóhannesson T, Belart JMC, Wuite J, Tolpekin V, Hannesdóttir K, Berthier E, Sigurðsson G, Einarsson B, Ófeigsson BG, Nagler T, Gudmundsson MT, Högnadóttir T.   +14 more
europepmc   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Late Holocene fast-ice dynamics around the Northern Victoria Land coast, Antarctica. [PDF]

Nat Commun
Tesi T, Weber ME, Muschitiello F, Dutta D, Belt ST, Pambianco C, Di Roberto A, Silva L, Gariboldi K, Morigi C, Battaglia F, Colizza E, De Santis L, Gallerani A, Aulicino G, Langone L, Giordano P.   +16 more
europepmc   +1 more source

Dual Single Atoms Boosting Photocatalytic Upcycling of Raw Polyvinylidene Fluoride Plastic

Advanced Materials, EarlyView.
To resolve the catastrophic disaster of plastic contamination, the Cu‐Fe dual‐single‐atom‐loaded In2P3S9 NSs photocatalyst was prepared for direct conversion of raw polyvinylidene fluoride plastic into valuable chemicals. The dual‐single‐atom catalyst exhibits exceptional performance, with a total acetic/formic acid production of ∼1351.8 µmol g−1 ...
Amin Talebian‐Kiakalaieh, Shiying Ren, Wenzhong Ji, Yun Liu, Bingquan Xia, Jingrun Ran, Shi‐Zhang Qiao   +6 more
wiley   +1 more source