Results 111 to 120 of about 102,620 (291)

Rheological control of crystal fabrics on Antarctic ice shelves

Journal of Glaciology
Ice crystal fabrics can exert significant rheological control on ice sheets and ice shelves, potentially softening or hardening anisotropic ice by several orders of magnitude compared to isotropic ice. We introduce an anisotropic extension of the Shallow
Nicholas M. Rathmann, David A. Lilien, Daniel H. Richards, Felicity S. McCormack, Maurine Montagnat   +4 more
doaj   +1 more source

Late Pleistocene glacial terminations accelerated by proglacial lakes [PDF]

Climate of the Past
During the glacial cycles of the past 800 000 years, Eurasia and North America were periodically covered by large ice sheets, causing up to 100 m of sea-level change.
M. D. W. Scherrenberg, C. J. Berends, R. S. W. van de Wal, R. S. W. van de Wal   +3 more
doaj   +1 more source

Feedbacks between ice and ocean dynamics at the West Antarctic Filchner-Ronne Ice Shelf in future global warming scenarios [PDF]

, 2016
The ice flow at the margins of the West Antarctic Ice Sheet is moderated by large ice shelves. Their buttressing effect substantially controls the mass balance of the WAIS and thus its contribution to sea level rise.
Goeller, Sebastian, Timmermann, Ralph
core  

Investigating the surface hydrology of Antarctic ice shelves using remote sensing and machine learning

, 2021
Rebecca Dell
openalex   +2 more sources

Bathymetric Control on Borchgrevink and Roi Baudouin Ice Shelves in East Antarctica [PDF]

, 2021
Hannes Eisermann, Graeme Eagles, Antonia Ruppel, Andreas Läufer, Wilfried Jokat   +4 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Antarctic ice-shelf meltwater outflows in satellite radar imagery: ground-truthing and basal channel observations

Journal of Glaciology
Ice shelves regulate the flow of the Antarctic ice sheet toward the ocean and its contribution to sea-level rise. Accurately monitoring the basal and surface melting of ice shelves is therefore essential for predicting the ice sheet's response to ...
Jakob Stanley Hamann, Thomas Arney, James David Kirkham, Paul Wachter, Karsten Gohl   +4 more
doaj   +1 more source

Firn air content changes on Antarctic ice shelves under three future warming scenarios [PDF]

The Cryosphere
The Antarctic firn layer provides pore space in which an estimated 94 % to 96 % of the surface melt refreezes or is retained as liquid water. Future depletion of firn pore space by increased surface melt, densification and formation of low-permeability ...
S. B. M. Veldhuijsen, S. B. M. Veldhuijsen, W. J. van de Berg, P. Kuipers Munneke, M. R. van den Broeke   +4 more
doaj   +1 more source