Results 111 to 120 of about 588,382 (370)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Advances in Climate Change ResearchWidespread supraglacial lakes (SGLs) across the Antarctic surface can accelerate land ice flow and be linked to ice shelf disintegration, further affecting sea-level rise projections. However, previous studies usually focused on SGLs at regional scale or
Xiao-Yi Shen +5 more
doaj +1 more source
Overview of areal changes of the ice shelves on the Antarctic Peninsula over the past 50 years [PDF]
The Cryosphere, 2010 In recent decades, seven out of twelve ice shelves around the Antarctic Peninsula (AP) have either retreated significantly or have been almost entirely lost. At least some of these retreats have been shown to be unusual within the context of the Holocene
A. J. Cook, D. G. Vaughan
doaj
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
A Simplified Three-Dimensional Ice-Sheet Model Including Ice Shelves [PDF]
Annals of Glaciology, 1990 We present a simplified numerical three-dimensional ice-sheet/ice-shelf model with a coarse horizontal resolution (100 km), designed for simulations of ice-volume changes on ice-age time scales (100 000 years and longer). The ice-sheet part uses the shallow-ice approximation to determine the flow, and includes a three-dimensional temperature ...
Böhmer, W., Herterich, K.
openaire +2 more sources
Reducing the uncertainty in projections of future ice shelf basal melting [PDF]
, 2014 Simulations of ice-shelf basal melting in future climate scenarios from the IPCC’s Fourth Assessment Report (AR4) have revealed a large uncertainty and the potential of a rapidly increasing basal mass loss particularly for the large cold-water ice ...
Hellmer, Hartmut +3 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Emperor penguins breeding on iceshelves [PDF]
, 2014 We describe a new breeding behaviour discovered in emperor penguins; utilizing satellite and aerial-survey observations four emperor penguin breeding colonies have been recorded as existing on ice-shelves.
Fretwell, Peter T. +3 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
NetCDF model output of the entire state of the surface layer, including simulated dFe dyes, of the circum-Antarctic [PDF]
, 2020 Dataset: Antarctic dFe model dyesFor a complete list of measurements, refer to the full dataset description in the supplemental file 'Dataset_description.pdf'.
Arrigo, Kevin R. +2 more
core +1 more source