Results 51 to 60 of about 268,002 (304)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Uncertainty Assessment of Ice Discharge Using GPR-Derived Ice Thickness from Gourdon Glacier, Antarctic Peninsula

open access: yesGeosciences, 2019
Ice cliffs within a glacier represent a challenge for the continuity equations used in many glacier models by interrupting the validity of input parameters. In the case of Gourdon Glacier on James Ross Island, Antarctica, a ∼300−500 m
Stefan Lippl   +5 more
doaj   +1 more source

Validation of SMOS sea ice thickness retrieval in the northern Baltic Sea [PDF]

open access: yes, 2015
The Soil Moisture and Ocean Salinity (SMOS) mission observes brightness temperatures at a low microwave frequency of 1.4 GHz (L-band) with a daily coverage of the polar regions.
Drusch, Matthias   +9 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Disk and circumsolar radiances in the presence of ice clouds [PDF]

open access: yes, 2016
The impact of ice clouds on solar disk and circumsolar radiances is investigated using a Monte Carlo radiative transfer model. The monochromatic direct and diffuse radiances are simulated at angles of 0 to 8° from the center of the sun.
A. Macke   +8 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Electrical Conductivities of Conductors, Semiconductors, and Their Mixtures at Elevated Temperatures

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents a comprehensive review of temperature‐dependent electrical conductivity data for multiple material classes at elevated temperatures, highlighting a persistent conductivity gap between metals and semiconductors in the range of 102$\left(10\right)^{2}$– 107$\left(10\right)^{7}$ S/m. Metal–ceramic irregular metamaterials are proposed
Valentina Torres Nieto, Marcia A. Cooper
wiley   +1 more source

Empirical sea ice thickness retrieval during the freeze-up period from SMOS high incident angle observations [PDF]

open access: yesThe Cryosphere, 2014
Sea ice thickness information is important for sea ice modelling and ship operations. Here a method to detect the thickness of sea ice up to 50 cm during the freeze-up season based on high incidence angle observations of the Soil Moisture and ...
M. Huntemann   +5 more
doaj   +1 more source

Kennicott Glacier, Alaska: Ice Thickness Measurements using Ground Penetrating Radar (and Inexperienced Skiiers) [PDF]

open access: yes, 2013
What happens when you send a professor, a mentor, and seven inexperienced undergraduates into the field? Dr. Erin Pettit and UAF graduate student Christina Carr led myself and six other undergraduates onto Kennicott Glacier in hopes of teaching us about
Albert, Sarah
core  

Joint inversion estimate of regional glacial isostatic adjustment in Antarctica considering a lateral varying Earth structure (ESA STSE Project REGINA) [PDF]

open access: yes, 2017
A major uncertainty in determining the mass balance of the Antarctic ice sheet from measurements of satellite gravimetry, and to a lesser extent satellite altimetry, is the poorly known correction for the ongoing deformation of the solid Earth caused by
Bamber, Jonathan L.   +11 more
core   +3 more sources

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