Results 51 to 60 of about 71,855 (305)

Vertex operators, solvable lattice models and metaplectic Whittaker functions

open access: yes, 2020
We show that spherical Whittaker functions on an $n$-fold cover of the general linear group arise naturally from the quantum Fock space representation of $U_q(\widehat{\mathfrak{sl}}(n))$ introduced by Kashiwara, Miwa and Stern (KMS).
Brubaker, Ben   +3 more
core   +1 more source

Coastal permafrost landscape development since the Late Pleistocene in the western Laptev Sea, Siberia [PDF]

open access: yes, 2011
The palaeoenvironmental development of the western Laptev Sea is understood primarily from investigations of exposed cliffs and surface sediment cores from the shelf.
Andreev, Andrei   +6 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

New ground ice maps for Canada using a paleogeographic modelling approach [PDF]

open access: yesThe Cryosphere, 2019
Ground ice melt caused by climate-induced permafrost degradation may trigger significant ecological change, damage infrastructure, and alter biogeochemical cycles. The fundamental ground ice mapping for Canada is now >20 years old and does not include
H. B. O'Neill, S. A. Wolfe, C. Duchesne
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hydrochemistry of hillslope permafrost catchments with degrading and stable ice-wedge polygons, Ogilvie Mountains, Yukon, Canada

open access: yesArctic Science
Ice-wedge polygonal terrain is one of the most widespread landscapes in continuous permafrost, and at many locations, is undergoing substantial degradation.
Emmanuel Carrière   +3 more
doaj   +1 more source

Creep Buckling of a Wedge-Shaped Floating Ice Plate

open access: yesEngineering Transactions, 2004
The paper is concerned with the problem of creep buckling of a floating ice plate pressing against a rigid, vertical-walled, engineering structure of a finite length.
R. Staroszczyk, B. Hedzielski
doaj   +1 more source

Timing and drivers of mid- to late Holocene ice-wedge polygon development in the Western Canadian Arctic [PDF]

open access: yes, 2018
Ice-wedge polygon formation and development from low-centred to high-centred types are thought to be either linear processes acting on long time-scales or rapid shifts between different regimes.
Fritz, Michael   +4 more
core  

The WISDOM Radar: Unveiling the Subsurface Beneath the ExoMars Rover and Identifying the Best Locations for Drilling [PDF]

open access: yes, 2017
The search for evidence of past or present life on Mars is the principal objective of the 2020 ESA-Roscosmos ExoMars Rover mission. If such evidence is to be found anywhere, it will most likely be in the subsurface, where organic molecules are shielded ...
Alain Herique   +33 more
core   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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