Results 21 to 30 of about 984 (123)
Locus-specific biochemical epigenetics/chromatin biochemistry by insertional chromatin immnoprecipitation (iChIP) [PDF]
Epigenetics & Chromatin, 2013 Comprehensive understanding of mechanisms of epigenetic regulation requires identification of molecules bound to genomic regions of interest in vivo. However, nonbiased methods to identify molecules bound to specific genomic loci in vivo are limited. To perform biochemical and molecular biological analysis of specific genomic regions, we developed the ...
Fujita, Toshitsugu, Fujii, Hodaka
openaire +1 more source
Microorganisms, 2022 The phylum Planctomycetota is known for having uncommon biological features. Recently, biotechnological applications of its members have started to be explored, namely in the genus Stieleria.
Inês Rosado Vitorino +5 more
doaj +1 more source
Cultivation strategies for prokaryotes from extreme environments
iMeta, Volume 2, Issue 3, August 2023., 2023 Schematic of targeted microbial cultivation strategies. Information from multi‐omics approaches can be combined with other techniques and innovative cultivation methods to provide the framework necessary for rationally designing targeted cultivation strategies.
Zi‐Wen Yang +5 more
wiley +1 more source
New antibiotics against bacterial resistance
Infectio, 2019 La evolución de la resistencia bacteriana ha generado un serio problema de salud pública debido al uso indiscriminado antibioticos, la aplicación de dosis no óptimas, la irregularidad en la toma de medicinas prescritas por el profesional de la salud han
Lorena Liseth Cárdenas
doaj +1 more source
SAT0590 SLE-Keytm Rule-Out Serlogic Test for SLE Using the Immunarray ICHIP™ [PDF]
Annals of the Rheumatic Diseases, 2015 Background SLE is associated with a large spectrum of autoantibodies, but currently there is no serologic diagnosis. Each autoantibody individually fails to discriminate with sufficient specificity and/or sensitivity SLE patients from healthy controls or from subjects afflicted with other autoimmune diseases.
I. Cohen +6 more
openaire +3 more sources
Current Status and Potential Applications of Underexplored Prokaryotes
Microorganisms, 2019 Thousands of prokaryotic genera have been published, but methodological bias in the study of prokaryotes is noted. Prokaryotes that are relatively easy to isolate have been well-studied from multiple aspects.
Kian Mau Goh +7 more
doaj +1 more source
Molecular Medicine, 2017 More than 100 risk loci for rheumatoid arthritis (RA) have been identified in individuals of European and Asian descent, but the genetic basis for RA in African Americans is less well understood.
Maria I. Danila +10 more
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Discovery of New Secondary Metabolites from Marine Bacteria Hahella Based on an Omics Strategy
Marine Drugs, 2022 Hahella is one characteristic genus under the Hahellaceae family and shows a good potential for synthesizing new natural products. In this study, we examined the distribution of the secondary metabolite biosynthetic gene cluster (SMBGC) under Hahella ...
Shufen He +10 more
doaj +1 more source
Template Activating Factor-I α Regulates Retroviral Silencing during Reprogramming
Cell Reports, 2019 Summary: Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is accompanied by dramatic changes in epigenetic programs, including silencing of endogenous and exogenous retroviruses. Here, we utilized replication-defective and persistent
Phuong Linh Bui +12 more
doaj +1 more source
Bio-Protocol, 2017 We have developed locus-specific chromatin immunoprecipitation (locus-specific ChIP) technologies consisting of insertional ChIP (iChIP) and engineered DNA-binding molecule-mediated ChIP (enChIP).
Toshitsugu Fujita, Hodaka Fujii
doaj +1 more source