AbstractThe in situ application of iChip cultivation in mangrove sediment from Hainan province, China, led to the isolation of a novel bacterial species Gallaecimonas mangrovi HK‐28. The extract of G. mangrovi HK‐28 exhibited antibiotic activity against the aquatic pathogen Vibrio harveyi, and its chemical constituents were further investigated by ...
Lijian Ding +12 more
openaire +3 more sources
Estimation of Ichip-heritability of inflammatory bowel diseases from immunochip case-control data [PDF]
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Alizadeh, Behrozziad +25 more
openaire +3 more sources
The future of antibiotics?- ichip and teixobactin-a review [PDF]
Sandra Sagar, Ezhilarasan D, Sagar Moses
openaire +2 more sources
The adaptation chip: repurposing the principles of the ichip for guiding in situ experimental evolution. [PDF]
Abstract Soil microbial ecosystems are complex and difficult to replicate in laboratory settings. It is often unclear which pressures most strongly shape microbial survival and evolution in situ, and new methods are needed to intersect the manipulative power of the lab with the reality of field environments.
Kaminsky LM +3 more
europepmc +2 more sources
Signal Amplification for Fluorescent Staining of Single Particles in Liquid Biopsies: Circulating Tumour Cells and Extracellular Vesicles. [PDF]
ABSTRACT Immunofluorescence (IF) staining represents a convenient and cost‐effective approach to analysing single extracellular vesicles (EVs) and identifying subpopulations with specific roles or biological functions. However, the application of the method is challenged by the weak and unstable signals generated by the low abundant markers carried by ...
Cavallaro S +13 more
europepmc +2 more sources
Use of Ichip for High-Throughput In Situ Cultivation of “Uncultivable” Microbial Species [PDF]
ABSTRACT One of the oldest unresolved microbiological phenomena is why only a small fraction of the diverse microbiological population grows on artificial media. The “uncultivable” microbial majority arguably represents our planet's largest unexplored pool of biological and chemical novelty. Previously we showed that species from
D, Nichols +8 more
openaire +2 more sources
Chromatin unwinding state for in situ identification and lineage tracing of circulating tumor cells. [PDF]
The detection of circulating tumor cells (CTCs) through liquid biopsy offers a non‐invasive approach for accurately monitoring cancer dissemination and evaluating therapeutic efficiency. However, their rarity and heterogeneity limit conventional tumor antigen labelling‐based methods in identifying and tracing CTCs.
Ye B +32 more
europepmc +2 more sources
Novel and Conventional Isolation Techniques to Obtain Planctomycetes from Marine Environments
Bacteria from the distinctive Planctomycetes phylum are well spread around the globe; they are capable of colonizing many habitats, including marine, freshwater, terrestrial, and even extreme habitats such as hydrothermal vents and hot springs.
Inês Vitorino +5 more
doaj +1 more source
The phylum Planctomycetota is known for having uncommon biological features. Recently, biotechnological applications of its members have started to be explored, namely in the genus Stieleria.
Inês Rosado Vitorino +5 more
doaj +1 more source
Cultivation strategies for prokaryotes from extreme environments
Schematic of targeted microbial cultivation strategies. Information from multi‐omics approaches can be combined with other techniques and innovative cultivation methods to provide the framework necessary for rationally designing targeted cultivation strategies.
Zi‐Wen Yang +5 more
wiley +1 more source

